Characteristics | Univariate Analysis | Multivariate Analysis | ||||
---|---|---|---|---|---|---|
OR | 95%CI | P-Value | OR | 95%CI | P-value | |
Age, No.(%) | ||||||
  < 25 | 1 | [Reference] | NA | 1 | [Reference] | NA |
 25–39 | 0.542 | [0.464,0.632] | < 0.001 | 0.586 | [0.492–0.7] | < 0.001 |
 40–54 | 0.343 | [0.295,0.399] | < 0.001 | 0.362 | [0.304–0.433] | < 0.001 |
 55–69 | 0.239 | [0.204,0.280] | < 0.001 | 0.26 | [0.215–0.314] | < 0.001 |
  ≥ 70 | 0.206 | [0.166,0.255] | < 0.001 | 0.239 | [0.186–0.306] | < 0.001 |
Gender, No.(%) | ||||||
 Female | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Male | 2.134 | [1.971,2.311] | < 0.001 | 2.279 | [2.086–2.488] | < 0.001 |
Race, No.(%) | ||||||
 White | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Black | 0.378 | [0.308,0.464] | <0.001 | 0.551 | [0.442–0.68] | < 0.001 |
 Othera | 1.131 | [1.011,1.266] | 0.032 | 0.906 | [0.799–1.025] | 0.119 |
Marital status, No.(%) | ||||||
 Married | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Single | 1.446 | [1.330,1.572] | < 0.001 | 1.152 | [1.042–1.273] | 0.006 |
 Divorced | 0.835 | [0.723,0.964] | 0.014 | 1.05 | [0.898–1.223] | 0.533 |
 Widowed | 0.509 | [0.405,0.641] | < 0.001 | 0.885 | [0.684–1.131] | 0.339 |
 Separated | 0.725 | [0.464,1.134] | 0.159 | 0.646 | [0.39–1.016] | 0.072 |
 Partner | 1.036 | [0.410,2.618] | 0.941 | 0.782 | [0.251–1.982] | 0.636 |
Region, No.(%) | ||||||
 East | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Pacific Coast | 1.331 | [1.233,1.437] | < 0.001 | 1.309 | [1.203–1.425] | < 0.001 |
 Northern Plains | 1.068 | [0.930,1.227] | 0.35 | 1.124 | [0.966–1.303] | 0.126 |
 Southwest | 1.132 | [0.978,1.311] | 0.095 | 1.171 | [0.999–1.367] | 0.048 |
Histology, No.(%) | ||||||
 Classical type | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Follicular variant | 0.555 | [0.508,0.606] | < 0.001 | 0.552 | [0.502–0.606] | < 0.001 |
 Oxyphilic variant | 1.247 | [0.525,2.962] | 0.617 | 1.299 | [0.472–3.019] | 0.574 |
 Encapsulated variant | 0.254 | [0.112,0.573] | 0.001 | 0.316 | [0.123–0.661] | 0.006 |
 Tall-cell variant | 3.484 | [2.565,4.733] | < 0.001 | 2.002 | [1.405–2.825] | < 0.001 |
 Diffuse sclerosing variant | 2.01 | [1.193,3.387] | 0.009 | 1.472 | [0.802–2.581] | 0.193 |
Tumor size, No.(%) | ||||||
 <5 mm | 1 | [Reference] | NA | 1 | [Reference] | NA |
  ≥ 5 mm | 3.395 | [3.138,3.673] | < 0.001 | 3.634 | [3.328–3.969] | < 0.001 |
Extrathyroidal extension, No.(%) | ||||||
 No | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Yes | 6.792 | [6.157,7.493] | < 0.001 | 4.583 | [4.115–5.103] | < 0.001 |
Multifocality, No.(%) | ||||||
 Solitary tumor | 1 | [Reference] | NA | 1 | [Reference] | NA |
 Multifocal tumor | 2.96 | [2.756,3.180] | < 0.001 | 2.359 | [2.184–2.547] | < 0.001 |
Laterality. No.(%) | ||||||
 Unilateral | 1 | [Reference] | NA |  |  |  |
 Bilateral | 1.095 | [0.650,1.845] | 0.732 |  |  |  |