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Table 1 Characteristics of patients of PTMC with cervical LMN identified from the SEER database

From: Exploring risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: construction of a novel population-based predictive model

Characteristic

Total

(n = 33,285)

Cervical LMN (−) (n = 29,801)

Cervical LMN (+) (n = 3484)

p-value

Age, n(%)

   

< 0.001

 <25

1059 (3.182)

799 (2.681)

260 (7.463)

 

 25–39

7062 (21.217)

6004 (20.147)

1058 (30.367)

 

 40–54

13,173 (39.576)

11,849 (39.760)

1324 (38.002)

 

 55–69

9552 (28.698)

8863 (29.741)

689 (19.776)

 

  ≥ 70

2439 (7.328)

2286 (7.671)

153 (4.392)

 

Gender, n(%)

   

< 0.001

 Female

27,569 (82.827)

25,083 (84.168)

2486 (71.355)

 

 Male

5716 (17.173)

4718 (15.832)

998 (28.645)

 

Race, n(%)

   

< 0.001

 White

27,796 (83.509)

24,800 (83.219)

2996 (85.993)

 

 Black

2245 (6.745)

2147 (7.204)

98 (2.813)

 

 Othera

3244 (9.746)

2854 (9.577)

390 (11.194)

 

Marital status, n(%)

   

< 0.001

 Married

22,671 (68.112)

20,383 (68.397)

2288 (65.672)

 

 Single

6217 (18.678)

5349 (17.949)

868 (24.914)

 

 Divorced

2591 (7.784)

2369 (7.949)

222 (6.372)

 

 Widowed

1479 (4.443)

1399 (4.694)

80 (2.296)

 

 Separated

279 (0.838)

258 (0.866)

21 (0.603)

 

 Partner

48 (0.144)

43 (0.144)

5 (0.144)

 

Region, n(%)

   

< 0.001

 East

14,013 (42.100)

12,724 (42.697)

1289 (36.998)

 

 Pacific Coast

14,235 (42.767)

12,544 (42.093)

1691 (48.536)

 

 Northern Plains

2734 (8.214)

2467 (8.278)

267 (7.664)

 

 Southwest

2303 (6.919)

2066 (6.933)

237 (6.803)

 

Histology, n(%)

   

< 0.001

 Classical type

23,131 (69.494)

20,404 (68.468)

2727 (78.272)

 

 Follicular variant

9652 (28.998)

8986 (30.153)

666 (19.116)

 

 Oxyphilic variant

42 (0.126)

36 (0.121)

6 (0.172)

 

 Encapsulated variant

183 (0.550)

177 (0.594)

6 (0.172)

 

 Tall-cell variant

192 (0.577)

131 (0.440)

61 (1.751)

 

 Diffuse sclerosing variant

85 (0.255)

67 (0.225)

18 (0.517)

 

Tumorsize, n(%)

   

< 0.001

 <5 mm

17,298 (51.969)

16,377 (54.955)

921 (26.435)

 

  ≥ 5 mm

15,987 (48.031)

13,424 (45.045)

2563 (73.565)

 

ETE, n(%)

   

< 0.001

 No

31,288 (94.000)

28,585 (95.920)

2703 (77.583)

 

 Yes

1997 (6.000)

1216 (4.080)

781 (22.417)

 

Multifocality, n(%)

   

< 0.001

 Solitary tumor

21,618 (64.948)

20,174 (67.696)

1444 (41.447)

 

 Multifocal tumor

11,667 (35.052)

9627 (32.304)

2040 (58.553)

 

Laterality, n(%)

   

0.732

 Unilateral

33,144 (99.576)

29,676 (99.581)

3468 (99.541)

 

 Bilateral

141 (0.424)

125 (0.419)

16 (0.459)

 
  1. Note: aOthers include American Indian / Alaska native, Asian or Pacific islander
  2. Abbreviations: PTMC Papillary thyroid microcarcinoma, LNM lymph node metastasis, ETE Extrathyroidal extension
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