Suggestive evidence of the genetic association of TMOD1 and PTCSC2 polymorphisms with thyroid carcinoma in the Chinese Han population

Table 6 Summary of SNP–SNP interactions on the risk of thyroid carcinoma analyzed by MDR method

Model	Training Bal. Acc	Testing Bal. Acc	CVC	OR (95% CI)	p
rs10982622	0.539	0.505	8/10	1.36 (1.06–1.74)	0.016
rs1052270, rs10982622	0.551	0.506	8/10	1.51 (1.17–1.95)	0.001
rs1052270, rs10982622, rs925489	0.577	0.510	5/10	1.83 (1.42–2.35)	< 0.0001
rs1052270, rs10982622, rs1475545, rs16924016	0.600	0.481	8/10	2.20 (1.70–2.85)	< 0.0001
rs1052270, rs10982622, rs1475545, rs16924016, rs925489^*	0.628	0.510	10/10	2.73 (2.12–3.52)	< 0.0001
rs1052270, rs10982622, rs1475545, rs16924016, rs925489, rs965513	0.630	0.505	10/10	2.78 (2.16–3.59)	< 0.0001

MDR: multifactor dimensionality reduction; Bal. Acc: balanced accuracy; CVC: cross-validation consistency; OR: odds ratio; 95% CI: 95% confidence interval
p < 0.05 indicates statistical significance. *: the best model in MDR analysis

ISSN: 1472-6823