Table 4 Clinical features, treatments, and outcomes of recurred or progressed cases
Case | Age (years) | Clinical features | Second therapy | Outcome (months)†|
|---|---|---|---|---|
13 | 21 | Virilization, amenorrhea, ascites, acanthosis nigricans, initial surgery delayed 4 years | PVB×4 | Continued and died (10) |
17 | 22 | Virilization, amenorrhea, with hereditary leiomyomatosis and renal cell carcinoma syndrome | RSO, RPLND | Not mentioned |
21 | 28 | Virilization, Cushing’s syndrome, hypertension, irregular menstruation | Metastatic lesions resection | Recurred (12), died (16) |
24 | 29 | Lower back and leg pain, normal reproductive hormone | Not mentioned | Died (6) |
38 | 46 | Ascites | Metastatic lesions resection, BEP | Tumor free (9) |
42 | 50 | Virilization | BEP×3, TP×8, chemotherapy invalid, GnRHa | No symptom (22 after first GnRHa) |
44 | 51 | Lower abdominal pain, vaginal spotting, anorexia | Not mentioned | Died |
51 | 58 | Virilization, pelvic discomfort | Increased dose of GnRHa | Not mentioned |
50 | 65 | Virilization, abdominal pain, ascites, bilateral lower limb edema | BEP×3 | Continued (18), lost to follow up |
56 | 93 | Virilization, abdominal pain, bilateral lower limb edema, aggressive and violent behavior | GnRHa & weekly paclitaxel for 1 month | Refused therapies and progressed |