Efficacy and safety of combination of empagliflozin and metformin with combination of sitagliptin and metformin during Ramadan: an observational study

Table 4 Comparison between Group A (Metformin + Sitagliptin) and Group B (Metformin + Empagliflozin)

Variables	Before/After Ramadan	Group A (n = 88) (Metformin + Sitagliptin)	Group B (n = 44) (Metformin + Empagliflozin)	P value
Age (years) mean ± SD		50.6 ± 10.5	44.7 ± 10.7	0.027*
Systolic BP (mmHg)	Before Ramadan	129.55 ± 15.2	122.8 ± 17.9	0.028*
Systolic BP (mmHg)	After Ramadan	128.9 ± 16.4	123.3 ± 16.4	0.065
Diastolic BP (mmHg)	Before Ramadan	81.1 ± 10.4	81.1 ± 8.7	0.711
Diastolic BP (mmHg)	After Ramadan	83.9 ± 14.7	85.0 ± 18.2	0.721
Weight (Kg)	Before Ramadan	77.6 ± 13.7	85.3 ± 7.8	0.007*
Weight (Kg)	After Ramadan	77.6 ± 4.0	80.5 ± 8.4	0.002*
BMI (Kg/m ² )	Before Ramadan	39.5 ± 5.7	36.5 ± 4.8	0.155
BMI (Kg/m ² )	After Ramadan	34.9 ± 4.8	33.7 ± 2.4	0.470
RBS (mg/dl)	Before Ramadan	209 ± 99	181 ± 64	0.005*
RBS (mg/dl)	After Ramadan	243 ± 44	162 ± 53	0.293
HbA1C (%)	Before Ramadan	7.8 ± 1.5	7.2 ± 0.8	0.038*
HbA1C (%)	After Ramadan	7.6 ± 1.6	6.9 ± 0.9	0.019*

BMI Body mass index, RBS Random blood sugar, BP Blood pressure
^*P value calculated using Independent sample T test, keeping P value ≤ 0.5 as significant

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