Hypoparathyroidism and late-onset hypogonadism in an adult male with familial 22q11.2 deletion syndrome: a case report with 3-year follow-up and review of the literature

Table 2 Imaging examination in this patient with 22q11.2 deletion syndrome

	Normal	2017	2019	2021
Enhanced MRI of pituitary	normal	Low signal nodule 0.4 cm in diameter	Low signal nodule 0.5 cm in diameter	-
Echocardiography	LA 28–32 mm LV 47 mm EF 61%	-	LA 36 mm LV 47 mm EF 61%	LA 39 mm LV 55 mm EF58%
Holter ECG of HRV	normal	moderate reduction	severe reduction	severe reduction
OSAHS	-	moderate	Severe	Severe
Thyroid ultrasound	normal	Right thyroid nodule (10 × 5 × 7 mm) nodular goiter?	Right thyroid nodule (13 × 8 × 10 mm nodular goiter?	-
Testicular Sonographic Color Doppler ultrasound	Bilateral testicles size 40 × 30 × 30 mm volume 15–20 ml	left testis size 20 × 15 × 33 mm volume 7 ml right testis size 23 × 16 × 31 mm volume 8 ml	left testis size 20 × 14 × 31 mm volume 6.1 ml right testis size 23 × 16 × 30 mm volume 7.8 ml	-

Abbreviations: ECG Electrocardiogram, MRI Magnetic resonance imaging, HRV Heart rate variability, OSAHS Obstructive sleep apnea hypopnea syndrome, LV Left ventricular, LA Left atrium, LVEF Left ventricular ejection fraction
- means that the laboratory data were not obtained

ISSN: 1472-6823