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Table 4 Associations between HbA1c and liver stiffness based on LSM value in patients with NAFLD

From: Association of glycated hemoglobin with non-alcoholic fatty liver disease patients and the severity of liver steatosis and fibrosis measured by transient elastography in adults without diabetes

 

Model 1

β (95% CI), P value

Model 2

β (95% CI), P value

Model 3

β (95% CI), P value

HbA1c

1.063 (0.293, 1.832) 0.007

1.470 (0.637, 2.304) < 0.001

0.461 (-0.337, 1.258) 0.258

Q1(4.1–5.1%)

Reference

Reference

Reference

Q2(5.2–5.4%)

0.043 (-0.832, 0.919) 0.922

0.135 (-0.745, 1.015) 0.764

-0.009 (-0.828, 0.811) 0.983

Q3(5.5–5.6%)

0.202 (-0.730, 1.134) 0.671

0.538 (-0.419, 1.495) 0.270

0.106 (-0.794, 1.007) 0.817

Q4(5.7–6.4%)

0.781 (-0.067, 1.628) 0.071

1.090 (0.193, 1.986) 0.017

0.275 (-0.572, 1.121) 0.525

P for trend

0.030

0.005

0.432

  1. Model 1: no covariates were adjusted
  2. Model 2: sex, age, and race were adjusted
  3. Model 3: sex, age, race, hypertension, smoking status, BMI, WC, activity level, hemoglobin, dyslipidemia, and HOMA-IR were adjusted
  4. Abbreviations: NAFLD Non-alcoholic fatty liver disease, HbA1c Glycosylated hemoglobin, BMI Body mass index, WC Waist circumference, HOMA-IR Homeostasis model assessment of insulin resistance
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BMC Endocrine Disorders

ISSN: 1472-6823

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