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Table 2 Multivariable odds ratio (OR) for NAFLD status based on HbA1c

From: Association of glycated hemoglobin with non-alcoholic fatty liver disease patients and the severity of liver steatosis and fibrosis measured by transient elastography in adults without diabetes

 

Model 1

OR (95% CI), P value

Model 2

OR (95% CI), P value

Model 3

OR (95% CI), P value

HbA1c

2.834 (2.321, 3.461)

< 0.001

2.900 (2.312, 3.637)

< 0.001

1.664 (1.284, 2.156)

< 0.001

Q1(4.1–5.1%)

Reference

Reference

Reference

Q2(5.2–5.4%)

1.225 (0.980, 1.532)

0.075

1.186 (0.944, 1.491)

0.143

1.136 (0.870, 1.484)

0.348

Q3(5.5–5.6%)

1.474 (1.161, 1.870)

0.001

1.403 (1.092, 1.804)

0.008

1.099 (0.820, 1.473)

0.528

Q4(5.7–6.4%)

2.606 (2.101, 3.234)

< 0.001

2.596 (2.043, 3.299)

< 0.001

1.620 (1.225, 2.142)

< 0.001

P for trend

< 0.001

< 0.001

< 0.001

  1. Model 1: no covariates were adjusted
  2. Model 2: sex, age, and race were adjusted
  3. Model 3: sex, age, race, hypertension, smoking status, BMI, WC, activity level, hemoglobin, dyslipidemia, and HOMA-IR were adjusted
  4. Abbreviations: NAFLD Non-alcoholic fatty liver disease, HbA1c Glycosylated hemoglobin, BMI Body mass index, WC Waist circumference, HOMA-IR Homeostasis model assessment of insulin resistance