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Table 5 Interaction between MC4R polymorphism and behavior and hormonal parameters on risk of obesity

From: Association and interaction of the MC4R rs17782313 polymorphism with plasma ghrelin, GLP-1, cortisol, food intake and eating behaviors in overweight/obese Iranian adults

Variable

TT a

CT

PInteraction

CC

PInteraction

High energy intake

1

0.62(0.1, 3.73)b

0.60

1.39 (1.08, 12.3)b

0.01

High fat intake

1

3.25 (0.24, 43.6)

0.37

23.43 (3.27, 167.9)

0.002

High carbohydrate intake

1

0.96 (0.12, 7.21)

0.97

6.85 (0.29, 191.8)

0.23

High protein intake

1

0.17 (0.02, 0.53)

0.01

1.59 (0.13, 19.32)

0.71

High physical activity

1

0.14 (0.02, 0.45)c

0.04

0.15 (0.01, 2.13)c

0.16

High emotional eating

1

17.99 (0.96, 336.5)

0.053

8.82 (1.35, 57.2)

0.02

High appetite

1

0.59 (0.02, 14.97)

0.75

1.55 (1.17, 11.19)

0.04

High anxiety

1

0.86 (0.01, 61.9)

0.94

0.66 (0.2, 78.1)

0.51

High depression

1

6.07 (0.17, 20.9)

0.31

38.8 (0.64, 132.4)

0.08

High stress

1

1.98 (0.73, 5.3)

0.17

4.31 (1.06, 17.4)

0.04

High ghrelin

1

0.05 (0.001, 5.1)

0.2

1.26 (1.04, 7.1)

0.03

High GLP-1

1

17.72 (0.48, 649.2)

0.11

0.89 (0.02, 40.06)

0.95

High cortisol

1

0.19 (0.005, 7.1)

0.37

1.09 (1, 8.87)

0.04

  1. Data are presented as Odds ratio and 95% confidence intervals after adjusted for age, gender, energy intake, PA
  2. a Reference group
  3. b adjusted for age, gender, PA
  4. c adjusted for age, gender, energy intake