Table 4 Association of MC4R variant rs17782313 with behavioral parameters
Variable | Group | Genotype | Crude | Model 1 | Model 2 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95%CI | p-value | OR | 95%CI | p-value | OR | 95%CI | P-value | |||
Emotional eating | Overweight | CT/TT CC/TT | 0.63 0.46 | (0.24, 1.60) (0.11, 1.23) | 0.33 0.12 | 0.44 0.65 | (0.16, 1.25) (0.24, 1.73) | 0.12 0.39 | 0.77 0.71 | (0.25, 2.33) (0.26, 1.91) | 0.65 0.50 |
Obese | CT/TT CC/TT | 0.40 1.09 | (0.13, 1.25) (1.02, 1.34) | 0.11 0.02 | 0.38 1.07 | (0.12, 1.20) (1.01, 1.28) | 0.09 0.01 | 0.30 1.07 | (0.08, 1.04) (1.01, 1.34) | 0.05 0.001 | |
Total | CT/TT CC/TT | 1.21 1.48 | (1.09, 1.44) (1.24, 1.95) | 0.001 0.03 | 1.21 1.48 | (1.09, 1.46) (1.24, 1.97) | 0.001 0.04 | 1.31 1.47 | (1.13, 1.71) (1.23, 1.98) | 0.001 0.04 | |
Depression | Overweight | CT/TT CC/TT | 0.41 1.67 | (0.06, 2.69) (0.36, 7.76) | 0.36 0.51 | 0.38 1.62 | (0.05, 2.53) (0.34, 7.63) | 0.34 0.50 | 0.45 1.63 | (0.06, 3.37) (0.33, 8.01) | 0.35 0.51 |
Obese | CT/TT CC/TT | 0.26 0.34 | (0.06, 1.12) (0.13, 0.88) | 0.07 0.02 | 0.25 0.34 | (0.05, 1.09( (0.12, 0.89) | 0.07 0.02 | 0.39 0.39 | (0.08, 1.86) (0.14, 1.07) | 0.08 0.01 | |
Total | CT/TT CC/TT | 0.23 0.58 | (0.08, 0.67) (0.27, 1.25) | 0.007 0.16 | 0.25 0.60 | (0.08, 0.73) (0.28, 1.29) | 0.01 0.19 | 0.36 0.68 | (0.11, 1.31) (0.31, 1.49) | 0.08 0.33 | |
Anxiety | Overweight | CT/TT CC/TT | 0.88 0.99 | (0.08, 8.95) (0.11, 8.67) | 0.91 0.99 | 0.82 1.06 | (0.07, 8.55) (0.11, 9.67) | 0.86 0.95 | 0.48 0.52 | (0.03, 6.66) (0.04, 5.74) | 0.58 0.59 |
Obese | CT/TT CC/TT | 3.34 0.96 | (0.32, 34.19) (0.10, 8.97) | 0.30 0.97 | 3.13 0.89 | (0.28, 34.59) (0.09, 8.52) | 0.35 0.92 | 4.19 0.61 | (0.25, 68.65) (0.05, 7.12) | 0.31 0.69 | |
Total | CT/TT CC/TT | 1.56 1.01 | (0.30, 8.03) (0.21, 4.76) | 0.59 0.98 | 1.54 1.07 | (0.29, 8.20) (0.22, 5.09) | 0.60 0.93 | 1.17 0.79 | (0.19, 7.21) (0.15, 3.98) | 0.85 0.77 | |
Stress | Overweight | CT/TT CC/TT | 0.08 0.80 | (0.008, 1.07) (0.21, 3.05) | 0.07 0.74 | 0.07 0.74 | (0.007, 1.03) (0.19, 2.93) | 0.06 0.67 | 0.06 0.66 | (0.004, 1.01) (0.15, 2.94) | 0.05 0.59 |
Obese | CT/TT CC/TT | 0.32 0.87 | (0.03, 3.28) (0.22, 3.35) | 0.33 0.84 | 0.20 0.75 | (0.01, 2.34) (0.17, 3.32) | 0.20 0.70 | 0.25 1.23 | (0.01, 3.42) (1.07, 1.95) | 0.30 0.04 | |
Total | CT/TT CC/TT | 0.15 0.86 | (0.03, 1.78) (0.33, 2.21) | 0.07 0.75 | 0.14 0.83 | (0.02, 1.18) (0.31, 2.17) | 0.07 0.70 | 0.20 0.96 | (0.03, 1.14) (0.35, 2.64) | 0.08 0.95 | |