Table 1 Comparison of perioperative outcomes
Outcomes | SGLT2-i (n = 31) | Matched Controls (n = 124) | p-value |
|---|---|---|---|
Metabolic acidosis with euglycemia, n, (%) | 7 (22.6) | 10 (8.1) | 0.047 |
Metabolic acidosis, n (%) | 7 (22.6) | 11 (8.9) | 0.054 |
ICU stay, hours, median [IQR] | 43.00 [21.00, 47.50] | 22.00 [18.00, 49.00] | 0.061 |
Blood gas analysis of the lowest pH at ICU admission | |||
Lowest pH, median [IQR] | 7.33 [7.30, 7.36] | 7.35 [7.31, 7.38] | 0.12 |
PaCO2, mmHg, median [IQR] | 41.00 [36.00, 44.65] | 43.45 [39.88, 47.02] | 0.013 |
Glucose, mg/dL, median [IQR] | 147.00 [123.00, 174.50] | 161.50 [124.75, 201.25] | 0.19 |
Lactate, mmol/L, median [IQR] | 1.39 [1.15, 1.81] | 1.30 [1.08, 1.80] | 0.71 |
Sodium, mEq/L, median [IQR] | 137.00 [134.80, 138.10] | 135.95 [134.17, 137.60] | 0.22 |
Potassium, mEq/L, median [IQR] | 4.28 [3.88, 4.54] | 4.08 [3.86, 4.30] | 0.15 |
Chloride, mEq/L, mean (SD) | 106.19 (4.06) | 104.94 (3.23) | 0.068 |
Bicarbonate, mEq/L, median [IQR] | 22.00 [18.55, 23.20] | 23.35 [21.70, 24.90] | < 0.001 |
Base excess, mmol/L. median [IQR] | -3.70 [-8.00, -2.05] | -2.55 [-3.90, -0.85] | 0.002 |
Anion gap, mEq/L, median [IQR] | 14.20 [11.45, 16.75] | 11.65 [9.60, 13.50] | 0.004 |