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Table 2 Baseline characteristics of different patient groups included in the study

From: Circulating miR-148b-3p and miR-27a-3p can be potential biomarkers for diagnosis of pre-diabetes and type 2 diabetes: integrating experimental and in-silico approaches

Variable

Control

Diabetes patients

Pre-diabetes patients

P-value

Sex

 Female

7 (35.0%)

13 (65.0%)

9 (45.0%)

0.197

 Male

13 (65.0%)

7 (35.0%)

11 (55.0%)

Age groups (years)

  ≤ 45

39.33 ± 2.12

40.6 ± 3.78

40.83 ± 3.6

0.68

 46–60

50.5 ± 4.59

51.88 ± 4.40

53.85 ± 5.33

  > 61

63.8 ± 3.03

66.16 ± 2.63

65 ± 2.51

BMI groups (kg/m2)

  ≤ 25

23.36 ± 1.48

23.68 ± 1.25

23.29 ± 1.44

0.19

 25–30

26.59 ± 1.24

27.32 ± 1.17

27.82 ± 1.21

  > 30

32.19 ± 1.40

33.68 ± 2.76

35.2 ± 4.41

BP (mm Hg)

12.80 ± 1.60

12.58 ± 1.66

11.74 ± 1.52

0.070

FBG (mg/dl)

89.95 ± 7.76

166.05 ± 68.26b

104.35 ± 8.73b

 < 0.001***

HbA1c (%)

5.43 ± 0.36

8.01 ± 1.64a

5.87 ± 0.41b

 < 0.001***

TG (mg/dl)

132.60 ± 94.79

230.85 ± 100.54a

168.85 ± 72.25b

 < 0.001***

TC (mg/dl)

197.55 ± 38.62

197.85 ± 51.06

193.85 ± 31.67

0.987

HDL (mg/dl)

47.09 ± 14.37

45.71 ± 12.95

46.07 ± 9.41

0.782

LDL (mg/dl)

124.20 ± 33.82

103.61 ± 44.55

116.90 ± 26.17

0.261

Cr (mg/dl)

1.01 ± 0.10

1.13 ± 1.07

1.03 ± 0.18

0.043

BUN (mg/dl)

13.95 ± 2.42

15.20 ± 3.82

15.40 ± 3.60

0.486

  1. Numeric data are expressed as Mean ± SD and were compared by the Kruskal–Wallis test and Chi-square test. Categorical data were summarized as frequency (percentage) and were compared by chi-square test
  2. BMI Body mass index, BP Blood pressure, HbA1c glycated hemoglobin, TG Triglyceride, TC Total cholesterol, HDL-C High-density lipoprotein cholesterol, LDL Low-density lipoprotein cholesterol, Cr Creatinine, BUN Blood urea nitrogen.
  3. a P < 0.05 Control vs. Diabetes patients
  4. b P < 0.05 Control vs. Pre-diabetes patients