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Fig. 2 | BMC Endocrine Disorders

Fig. 2

From: Circulating miR-148b-3p and miR-27a-3p can be potential biomarkers for diagnosis of pre-diabetes and type 2 diabetes: integrating experimental and in-silico approaches

Fig. 2

ROC curves analysis of plasma miR-27a-3p and miR-148b-3p for discrimination between the cases of prediabetic, diabetics and the control group. The area under the curve of miR-27a-3p can differentiate the diabetic patients from the control group with an AUC of 0.71 (95% CI 0.53–0.89, P = 0.02), while the AUC for discriminating the pre-diabetics from the control group is 0.56 (95% CI 0.37–0.74, P = 0.51) and the AUC for discriminating the pre-diabetics from the diabetics is 0.67 (95% CI 0.48–0.85, P = 0.06).For miR-148b-3p AUC is of 0.87 (95% CI 0.74–0.99, P < 0.0001) for discriminating the T2D patients from the control subjects,for discriminating the pre-diabetic patients from the control group the AUC is 0.74 (95% CI 0.56–0.91, P = 0. 009) and the AUC of 0.78 (95% CI 0.64–0.92, P = 0.002) can differentiate the pre-diabetic from the diabetic patients

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BMC Endocrine Disorders

ISSN: 1472-6823

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