Table 3 Previously published clinical decision points of the TSI assay
Author | Source of subjects | Publication year | Sample size of new-onset GD | Sample size of control | Cut-off points (IU/L) | Sensitivity | Specificity |
|---|---|---|---|---|---|---|---|
Frank et al.[17] | Germany | 2015 | 27 | 325 | 0.54 | 99.8% | 99.1% |
Allelein et al.[24] | Germany | 2016 | 30 | 221 | 0.55 | 100% | 98.0% |
Tozzoli et al.[15] | Italy | 2016 | 72 | 311 | 0.54 | 100% | 98.7% |
Villalta et al.[19] | Italy | 2018 | 57 | 333 | 0.55 | 100% | 98.2% |
Autilio et al.[16] | Italy | 2018 | 46 | 99 | 0.57 | 98.0% | 99.0% |
Scappaticcio et al.[25] | Switzerland | 2020 | 86 | 38 | 0.1 | 94.2% | 84.2% |
Cheng et al.[18] | China | 2021 | 100 | 803 | 0.42 | 100% | 97.1% |
Our study | China | 2021 | 227 | 109 | 0.577 | 96.92% | 97.25% |