Skip to main content

Table 2 Biochemical characteristics of adolescent PCOS subjects stratified by BMI

From: Dysglycemia screening with oral glucose tolerance test in adolescents with polycystic ovary syndrome and relationship with obesity

 

BMI < 95th percentile (N = 34)

Median [IQR]

BMI > 95th percentile (N = 72)

Median [IQR]

P

Age at time of OGTT

16.1 [15.6–16.8]

15.2 [13.3–16.1]

0.002**

BMI (kg/m2)

25.4 [23.5–27.6]

34.7 [30.6–38.1]

< 0.001***

BMI z-score

1.15 [0.87–1.43]

2.17 [1.95–2.38]

< 0.001***

HbA1c level (%) (N = 89)

5.40 [5.10–5.53]

5.50 [5.20–5.80]

0.147

Results of OGTT

  

0.325

 Normal

30 (88.2%)

54 (75.0%)

 

 Impaired Glucose Tolerance

4 (11.7%)

17 (23.6%)

 

 Type 2 Diabetes Mellitus

0 (0.00%)

1 (1.4%)

 

2-hour glucose level (mg/dl)

97.0 [84.8–111.0]

116 [96.0–138.0]

0.005**

HOMA-IR (N = 103)

1.79 [1.04–2.36]

4.02 [2.82–5.94]

< 0.001***

WBISI (N = 103)

5.13 [3.90–8.64]

2.00 [1.23–3.21]

< 0.001***

Total testosterone (ng/dl) (N = 102)

44.0 [26.5–53.5]

45.0 [37.0–56.0]

0.293

Free testosterone (ng/dl) (N = 78)

4.70 [2.30–8.25]

7.90 [3.92–11.0]

0.026*

LH/FSH ratio (N = 94)

2.19 [0.94–2.68]

1.54 [1.00–2.30]

0.328

LH/FSH diagnostic (N = 94)

  

0.028*

 <= 2

13 (43%)

43 (67%)

 

 > 2

17 (57%)

21 (33%)

 
  1. IQR Interquartile range, OGTT Oral Glucose Tolerance Test, BMI Body Mass Index, HbA1c Hemoglobin A1c, HOMA-IR Homeostasis Model Assessment, WBISI Whole Body Insulin Sensitivity Index
  2. ***P ≤ 0.001, **P ≤ 0.01, *P ≤ 0.05