Fig. 4
From: Effects of high-fat diet on thyroid autoimmunity in the female rat
HFD disturbed the PD-1 signaling in thyroid and serum. A, B Representative images of PD-1 and PD-L1 staining in the thyroid (5 rats per group). Each right-hand panel (× 400) depicts a magnified image of the boxed area of the corresponding image in the left panel (× 100). C Relative mRNA expression of PD-1 and PD-L1 in the thyroid (n = 5). D Serum expression of sPD-1 and sPD-L1 (n = 10). Values were mean ± SEM; *p < 0.05, and ***p < 0.001; ns, no statistical significance