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Table 1 Demographic characteristic and biochemical analysis in diabetic patients with and without retinopathy

From: Alterations in circulating levels of vitamin D binding protein, total and bioavailability of vitamin D in diabetic retinopathy patients

Demographic characteristic

Diabetic Mellitus with retinopathy (N = 62)

Diabetic Mellitus without retinopathy and/or nephropathy (N = 92)

p-value

Age (years)a

59.6 ± 6.0

55.0 ± 6.0

0.001

Sex ( Women)c

27 (43.5%)

53 (57.6%)

0.1

BMI (kg/m2)a

28.9 ± 4.6

29.0 ± 5.6

0.8

Disease duration (year)a

16.5 ± 6.7

10.1 ± 6.2

0.001

Vitamin D deficiency or insufficiency (< 30 ng/ml)

51 (83.6%)

70 (77.8%)

0.4

Laboratory outcomes

 FBS (mg/dL)a

150.1 ± 64.4

143.6 ± 46.2

0.45

 Ln BUN (mg/dL)a

3.1 ± 0.4

2.7 ± 0.3

0.001

 Uric acid (mg/dL)a

5.62 ± 1.57

5.10 ± 1.33

0.02

 TG (mg/dL)a

133.42 ± 68.05

157.82 ± 94.17

0.05

 TC (mg/dL)a

155.67 ± 40.71

152.82 ± 36.76

0.6

 HDL (mg/dL)a

42.19 ± 10.13

49.00 ± 10.33

0.001

 LDL (mg/dL)a

86.25 ± 25.91

81.56 ± 23.82

0.23

 eGFR (mL/min)a

69.80 ± 30.10

92.69 ± 27.11

0.001

 Cr (mg/dL)a

1.5 ± 0.9

1.1 ± 0.5

0.001

 Albumin (g/dL)a

5.07 ± 0.55

5.26 ± 0.96

0.1

 Ln Insulin ( (μU/L)a

2.45 ± 0.93

2.27 ± 0.65

0.2

 Urine microalbumin (mg/L)a

184.11 ± 45.87

8.36 ± 0.97

0.001

 25(OH)D (ng/mL)a

18.5 ± 11.6

21.4 ± 10.2

0.08

 Ln PTH (pg/mL)a

3.8 ± 0.6

3.5 ± 0.4

0.01

 Vitamin D bioavailability (ng/ml)b

1.7 (3.04)

0.86 (2.2)

0.03

  1. BMI Body mass index, BUN Blood urea nitrogen, Cr Creatinine, eGFR Estimating glomerular filtration rate, FBS Fasting blood serum, HDL High-density lipoprotein, LDL Low-density lipoprotein, Ln Natural logarithm, PTH Parathyroid hormone
  2. amean ± SD
  3. bmedian (IQR)
  4. cNumber (percentage)