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Table 1 Comparison of the clinical characteristics according to APOA2 polymorphism

From: Dietary acid load modifies the effects of ApoA2–265 T > C polymorphism on lipid profile and serum leptin and ghrelin levels among type 2 diabetic patients

 

APOA2–265 T > C

P value*

N

TT = 289

(TC + CC) = 438

Age (year)

53.78 ± 6.76

54.26 ± 6.49

0.33

Alcohol (Yes)

8 (33.3%)

16 (66.7%)

0.36

Smoking (Yes)

53 (39.3%)

82 (60.7%)

0.24

BMI (kg/m2)

29.31 ± 4.65

29.39 ± 4.78

0.82

WC (cm)

92.19 ± 10.36

92.32 ± 10.72

0.86

Physical activity (MET min/week)

37.85 ± 5.54

37.74 ± 5.42

0.79

Total energy intake (kcal/day)

2519.08 ± 844.92

2526.81 ± 938.86

0.91

Protein (gr/day)

90.21 ± 34.16

90.33 ± 36.45

0.96

Carbohydrate (gr/day)

339.53 ± 138.03

345.15 ± 145.92

0.59

Total fat (gr/day)

103.02 ± 46.72

103.76 ± 48.45

0.83

Phosphor (mg/day)

1677.47 ± 620.64

1683.84 ± 605.14

0.88

Magnesium (mg/day)

511.84 ± 227.72

508.27 ± 223.94

0.82

Potassium (mg/day)

4278.43 ± 1619.34

4343.19 ± 1732.50

0.6

Calcium (mg/day)

1153.31 ± 424.16

1168.80 ± 434.83

0.62

EER.(Men)

2600.70 ± 282.01

2572.46 ± 275.94

0.41

EER.(Women)

2020.54 ± 181.43

2022.1028 ± 183.50

0.93

NEAP (mEq/day)

−9.01 ± 0.26

−9.03 ± 0.24

0.26

PRAL (mEq/day)

−10.89 ± 21.37

−11.43 ± 22.54

0.74

TC (mg/dl)

203.45 ± 70.5

196.04 ± 72.29

0.21

HDL-C (mg/dl)

52.67 ± 11.02

53.77 ± 13.72

0.52

LDL-C (mg/dl)

111.6 ± 34.64

109.61 ± 76.36

0.70

TG (mg/dl)

184.89 ± 104.70

185.43 ± 109.28

< 0.001*

Ghrelin (ng/ml)

2.16 ± 0.83

2.44 ± 1.48

0.02*

Leptin (ng/ml)

24.51 ± 14.04

25.18 ± 14.71

0.73

hs-CRP (mg/l)

1.82 ± 1.23

2.48 ± 1.58

0.006*

TAC (g/dl)

2.51 ± 0.56

2.45 ± 0.56

0.53

SOD (U/ml)

0.14 ± 0.04

0.14 ± 0.04

0.29

IL-18 (pg /ml)

247.68 ± 33.83

249.36 ± 29.16

0.73

PGF2α (pg/ml)

71.60 ± 5.92

73 ± 6.19

0.16

PTX 3 (ng/ml)

2.81 ± 0.45

2.52 ± 0.46

< 0.001*

AIP

0.49 ± 0.24

0.48 ± 0.24

0.87

AC

3 ± 1.6

2.85 ± 1.77

0.23

CRI-II

2.08 ± 0.65

2.07 ± 0.67

0.93

CR-I

4 ± 1.6

3.85 ± 1.77

0.23

  1. Values are means ± SD Independent T. test (Pvalue*). BMI Body mass index, WC Waist circumference, EER Estimated Energy Requirement, TG Triglyceride, TC Total cholesterol, hs-CRP High sensivity c-reactive protein, TAC Total antioxidant capacity, SOD Superoxide Dismutase, IL18 Interleukin 18, PGF2α Prostaglandin F2α. Atherogenic Index of Plasma (AIP) = log (TG/HDL-C), Atherogenic Coefficient (AC) = (TC-HDL-C)/HDL-C, Castelli’s Risk Index II (CRI-II) = (LDL/HDL), Castelli’s Risk Index I (CRI-I) = (TC/HDL-C)