Fig. 6From: Tumor-induced osteomalacia characterized by “painful knee joint with difficulty in moving”: a case reportImmunohistochemisty for Vim, CD34, Desmin, and S100 of the tumor (100×). A Vim, as a mesenchymal cell marker, is positive in most tumor cells, indicating the tumor originated from mesenchymal tissues (brown). B The tumor contains a large number of small capillaries, most of which are positive for CD34 staining (brown) whereas tumor cells are negative. C Desmin is characteristically found in muscle cells and associated neoplasms, is negative in PMT. D S100 is the specific protein of neural crest-derived tumors, is negative in PMTBack to article page