Fig. 2

A family tree of the patient and the results of genetic testing in the patient and her family. A Squares, circles, and arrows indicate males, females, and proband, respectively. Family members, including I-1, II-1, II-3, had a history of hypercalcemia. d. Diseased. M and N, CASR wild type and p. Pro55Leu mutation alleles, respectively. Roman numerals on the left of the pedigrees indicate generation number, and the numbers below the symbols indicate the subject's number within each pedigree. The arrow shows the proband. B Sequence analysis of this family. M and N, CASR wild type and p. Pro55Leu mutation alleles, respectively. The arrow shows this mutation site (c.164). The half-filled symbols indicate the individuals with FHH