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Table 1 Criteria currently in use to define metabolic health

From: Prevalence rates of metabolic health and body size phenotypes by different criteria and association with insulin resistance in a Maltese Caucasian population

  NCEP-ATPIII [ 10] Wildman et al. [11] Doumatey et al. [12] Hamer et al. [13] Aguilar-Salinas et al. [14] Lynch et al. [15] Karelis et al. [16] Harmonisation criteria (Lavie et al.) [17]
BP (mmHg) SBP ≥ 130 or DBP ≥ 85 or on Rx SBP ≥ 130or DBP ≥ 85 or on Rx SBP > 130or DBP > 85 or not on Rx SBP ≥ 130 or DBP ≥ 85 or on Rx SBP ≥ 140 or DBP < 90 or not on Rx SBP > 130or DBP > 85 & not on Rx   SBP ≥ 130 or DBP ≥ 85 or on Rx
TG (mmol/L) ≥1.69 mmol/L ≥ 1.70      ≥1.70 ≥ 1.70
HDL-C (mmol/L) HDL-C < 1.03 mmol/L in men or < 1.29 mmol/L in women or on Rx <1.04 in men or < 1.30 on women <1.03 in men or < 1.29 in women <1.03 in men or < 1.30 in women < 1.00   <1.30 & not on Rx <1.0 in men or < 1.30 in women
TG/HDL ratio       >1.65 in men or > 1.32 in women & not on Rx   
LDL-C (mmol/L)        ≥2.60  
T. Chol (mmol/L)        ≥5.20  
FPG (mmol/L) ≥ 5.6 or on Rx ≥ 5.55 or on Rx ≤7.0 Presence of diabetes ≥7.0 or on Rx    ≥ 5.6 or on Rx
WC (cm) >102 in men and > 88 in women    >102 in men or > 88 in women     
HOMA-IR   >5.13      <1.95  
hsCRP (ng/L)   >0.1   >3.0     
No. of criteria required to characterize the metabolically healthy phenotype 0, ≤ 1 or ≤ 2 <2 of the above None of the above < 2 of the above None of the above None of the above ≤ 1 of the above None of the above
  1. The criteria used by Meigs et al. [18] are the same as NCEP-2
  2. hsCRP high-sensitivity C-reactive protein, HDL-C high density lipoprotein cholesterol, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, LDL-C Low density lipoprotein cholesterol, NCEP-ATP111 National Cholesterol Education Program-Adult Treatment Panel III criteria, Rx treatment, TG triglycerides, WC waist index