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Table 1 Criteria currently in use to define metabolic health

From: Prevalence rates of metabolic health and body size phenotypes by different criteria and association with insulin resistance in a Maltese Caucasian population

 

NCEP-ATPIII [ 10]

Wildman et al. [11]

Doumatey et al. [12]

Hamer et al. [13]

Aguilar-Salinas et al. [14]

Lynch et al. [15]

Karelis et al. [16]

Harmonisation criteria (Lavie et al.) [17]

BP (mmHg)

SBP ≥ 130 or DBP ≥ 85 or on Rx

SBP ≥ 130or DBP ≥ 85 or on Rx

SBP > 130or DBP > 85 or not on Rx

SBP ≥ 130 or DBP ≥ 85 or on Rx

SBP ≥ 140 or DBP < 90 or not on Rx

SBP > 130or DBP > 85 & not on Rx

 

SBP ≥ 130 or DBP ≥ 85 or on Rx

TG (mmol/L)

≥1.69 mmol/L

≥ 1.70

    

≥1.70

≥ 1.70

HDL-C (mmol/L)

HDL-C < 1.03 mmol/L in men or < 1.29 mmol/L in women or on Rx

<1.04 in men or < 1.30 on women

<1.03 in men or < 1.29 in women

<1.03 in men or < 1.30 in women

< 1.00

 

<1.30 & not on Rx

<1.0 in men or < 1.30 in women

TG/HDL ratio

     

>1.65 in men or > 1.32 in women & not on Rx

  

LDL-C (mmol/L)

      

≥2.60

 

T. Chol (mmol/L)

      

≥5.20

 

FPG (mmol/L)

≥ 5.6 or on Rx

≥ 5.55 or on Rx

≤7.0

Presence of diabetes

≥7.0 or on Rx

  

≥ 5.6 or on Rx

WC (cm)

>102 in men and > 88 in women

  

>102 in men or > 88 in women

    

HOMA-IR

 

>5.13

    

<1.95

 

hsCRP (ng/L)

 

>0.1

 

>3.0

    

No. of criteria required to characterize the metabolically healthy phenotype

0, ≤ 1 or ≤ 2

<2 of the above

None of the above

< 2 of the above

None of the above

None of the above

≤ 1 of the above

None of the above

  1. The criteria used by Meigs et al. [18] are the same as NCEP-2
  2. hsCRP high-sensitivity C-reactive protein, HDL-C high density lipoprotein cholesterol, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, LDL-C Low density lipoprotein cholesterol, NCEP-ATP111 National Cholesterol Education Program-Adult Treatment Panel III criteria, Rx treatment, TG triglycerides, WC waist index