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Table 2 Change after medical nutrition therapy

From: Improvement of beta-cell function in conjunction with glycemic control after medical nutrition therapy in newly-diagnosed type 2 diabetes mellitus

 

At baseline

After MNT

P value

Overall population (n = 68)

 HbA1c (%)

9.6 ± 1.8

7.2 ± 1.0

 < 0.001

   (mmol/mol)

81 ± 20

55 ± 11

 

 Body mass index (kg/m2)

26.9 ± 4.1

25.4 ± 3.7

 < 0.001

 Disposition index (unit)

0.34 (0.20–0.68)

0.88 (0.53–1.52)

 < 0.001

 Matsuda’s insulin sensitivity index (unit)

4.70 (2.95–5.93)

5.17 (3.48–6.89)

0.003

Baseline HbA1c ≥ 9% (75 mmol/mol) (n = 39)

 HbA1c (%)

10.8 ± 1.2

7.5 ± 1.1

 < 0.001

   (mmol/mol)

95 ± 14

58 ± 12

 

 Body mass index (kg/m2)

26.8 ± 4.0

25.3 ± 3.3

 < 0.001

 Disposition index (unit)

0.25 (0.17–0.37)

0.87 (0.48–1.48)

 < 0.001

 Matsuda’s insulin sensitivity index (unit)

4.69 (3.25–5.82)

5.35 (3.85–7.17)

0.031

Baseline HbA1c < 9% (75 mmol/mol) (n = 29)

 HbA1c (%)

7.9 ± 0.7

6.9 ± 0.7

 < 0.001

   (mmol/mol)

62 ± 8

52 ± 7

 

 Body mass index (kg/m2)

27.0 ± 4.2

25.6 ± 4.1

 < 0.001

 Disposition index (unit)

0.62 (0.39–0.78)

1.00 (0.69–1.51)

 < 0.001

 Matsuda’s insulin sensitivity index (unit)

4.71 (2.42–6.18)

4.66 (2.75–6.47)

0.034

  1. Data are mean ± standard deviations or medians (interquartile ranges)
  2. MNT Medical Nutrition Therapy