Table 2 Behavioral and biochemical parameters of the study population across rs1801260 genotypes

Behavioral factors

 VAS. score

46 ± 18^ab

38 ± 19^a

28 ± 11^b

0.009

39 ± 19^ab

25 ± 18^a

17 ± 11^b

0.007

43 ± 19^ab

32 ± 21^a

21 ± 18^b

˂0.001

 ME. score

63 ± 7.6^ab

52 ± 6.9^a

47 ± 6.8^b

˂0.001

62 ± 8^ab

50 ± 6^a

47 ± 6^b

˂0.001

63 ± 7.7^ab

51 ± 7.7^a

47 ± 6.8^b

˂0.001

 Sleep (h/day)

8.3 ± 1^a

8 ± 0.9

7.7 ± 1.4^a

0.01

8.5 ± 1^a

8.1 ± 0.7

8 ± 0.6^a

˂0.001

8.4 ± 1^ab

8.1 ± 0.8^a

7.6 ± 0.9^b

˂0.001

 Food timing (h)

Breakfast

7.7 ± 0.9^ab

8.4 ± 0.9^a

9.4 ± 1.2^b

˂0.001

7.8 ± 0.8^ab

8.9 ± 1.1^a

9.2 ± 0.9^b

˂0.001

7.8 ± 0.9^ab

8.6 ± 1^a

9.3 ± 1^b

˂0.001

Lunch

13.7 ± 0.7^ab

14.2 ± 0.8^a

14.9 ± 0.9^b

˂0.001

13.7 ± 0.8^ab

14.7 ± 0.9^a

15.1 ± 1^b

˂0.001

13.7 ± 0.7^ab

14.5 ± 0.9^a

15.1 ± 0.9^b

˂0.001

Dinner

20.2 ± 0.8^a

20.8 ± 0.8

21.6 ± 0.6^a

˂0.001

20.2 ± 0.8^ab

21.2 ± 0.9^a

21.4 ± 0.9^b

˂0.001

20.2 ± 0.8^ab

21 ± 0.9^a

21.5 ± 0.8^b

˂0.001

Hormonal factors

 GLP-1 (pg/ml)

47.3 ± 19

60 ± 16

42.1 ± 22

0.28

61.1 ± 16^ab

54.1 ± 16.3^b

38.8 ± 19^b

0.02

53.3 ± 19^a

56.4 ± 16

40.4 ± 20^a

0.02

 Ghrelin (ng/ml)

0.84 ± 0.4

0.8 ± 0.1

0.78 ± 0.5

0.64

0.87 ± 0.2^a

0.92 ± 0.3

1.1 ± 0.9^ab

0.048

0.86 ± 0.3

0.87 ± 0.2

0.94 ± 0.7

0.98