Table 1 Clinical characteristics of patients
From: Primary hyperparathyroidism in Saudi Arabia revisited: a multi-centre observational study
Parameters | All | Riyadh | Al Ahsa | Jeddah |
|---|---|---|---|---|
N | 205 | 96 | 59 | 50 |
Age (years) | 59.8 ± 15.5 | 62.6 ± 15.2 | 59.0 ± 15.7 | 55.3 ± 14.9*! |
Female | 163 (79.5) | 84 (87.5) | 42 (71) | 37 (74) |
Mode | ||||
ER | 7 (3.7) | 3 (4) | 0 | 4 (8) |
In-patient | 19 (10.1) | 4 (5) | 14 (25) | 1 (2) |
Out-patient | 162 (86.2) | 77 (92) | 43 (75) | 42 (89) |
Positive for PTH scan | 171 (83.4) | 77 (80) | 51 (86) | 43 (86) |
Medical History | ||||
Obesity | 20 (9.8) | 4 (4) | 10 (17) | 6 (12) |
Diabetes Mellitus | 10 (4.9) | 4 (4) | 4 (7) | 2 (4) |
Dyslipidemia | 2 (1.0) | 1 (1) | 0 | 1 (0) |
Hypertension | 11 (5.4) | 7 (7) | 4 (7) | 0 |
Hypothyroidism | 5 (2.4) | 4 (4) | 1 (2) | 0 |
Thyroid nodule | 6 (2.9) | 5 (5) | 0 | 1 (2) |
Multiple | 103 (50.2) | 49 (51) | 32 (54) | 22 (44) *! |
Others | 16 (7.8) | 9 (9) | 3 (5) | 4 (8) |
None | 32 (15.6) | 13 (14) | 5 (8) | 14 (28) |
Clinical manifestations on admission | ||||
Renal | ||||
Hypercalciuria | 9 (4.4) | 3 (3) | 2 (3) | 4 (8) |
Kidney Stones | 32 (15.6) | 15 (16) | 11 (19) | 6 (12) |
Polyuria | 9 (4.4) | 5 (5) | 1 (2) | 3 (6) |
None | 154 (75.6) | 73 (76) | 45 (76) | 36 (72) |
Skeletal | ||||
Osteoporosis | 67 (32.7) | 42 (44) | 16 (27) | 9 (18) * |
Bone and joint pain | 34 (16.6) | 8 (8) | 14 (24) | 12 (24) |
Both | 31 (15.1) | 8 (8) | 8 (14) | 15 (30) |
None | 73 (35.6) | 38 (40) | 21 (36) | 14 (28) |
Gastrointestinal | ||||
Abdominal pain | 15 (7.3) | 5 (5) | 8 (14) | 2 (4) |
Anorexia | 5 (2.4) | 1 (1) | 3 (5) | 1 (2) |
Constipation | 10 (4.9) | 3 (3) | 1 (2) | 6 (12) |
Nausea/Vomiting | 2 (1.0) | 1 (1) | 1 (2) | 0 |
Peptic Ulcer | 1 (0.5) | 0 | 0 | 1 (2) |
Multiple symptoms | 22 (10.7) | 4 (4) | 8 (14) | 10 (20) * |
None | 150 (73.2) | 82 (85) | 38 (64) | 30 (60) |
Neuromuscular and Psychologic | ||||
Weakness/fatigue | 35 (17.1) | 6 (6) | 12 (24) | 15 (30) |
Depression | 5 (2.4) | 2 (2) | 2 (3) | 1 (2) |
Multiple symptoms | 18 (8.8) | 2 (2) | 3 (5) | 13 (26)*! |
None | 147 (71.7) | 86 (90) | 40 (68) | 21 (42) |
Cardiovascular | ||||
Hypertension | 90 (43.9) | 49 (51) | 21 (36) * | 20 (40) * |
LVH | 1 (0.5) | 1 (1) | 0 | 0 |
Bradycardia | 2 (1) | 1 (1) | 1 (2) | 0 |
Multiple symptoms | 18 (8.8) | 5 (5) | 13 (22) | 0 |
None | 94 (45.9) | 40 (42) | 24 (41) | 30 (60) |
Single | ||||
Left lower lobe | 6 (2.9) | 6 (6) | 0 * | 0 * |
Left upper lobe | 68 (33.2) | 27 (28) | 24 (41) | 17 (34) |
Right lower lobe | 72 (35.1) | 31 (32) | 25 (42) | 16 (32) |
Right upper lobe | 10 (4.9) | 7 (7) | 0 | 3 (6) |
None | 49 (23.9) | 25 (26) | 10 (17) | 14 (28) |
Bilateral | 15 (7.3) | 6 (6) | 2 (3) | 7 (14) |