Clinical diagnostic value of American College of Radiology thyroid imaging report and data system in different kinds of thyroid nodules

Table 7 Diagnostic performances of ACR score, ACR TI-RADS and Kwak TI-RADS in the diagnosis of MTC or PTC

Variables	AUC (95%CI)	Cutoff	Sensitivity (95%CI)	Specificity (95%CI)	PPV (95%CI)	NPV (95%CI)	Z	P	Z^*	P^*
ACR score^a	0.850 (0.811–0.891)	> 5	0.839 (0.717–0.924)	0.765 (0.709–0.815)	0.431 (0.709–0.815)	0.957 (0.709–0.815)	2.404	0.016
ACR TI-RADS^a	0.820 (0.773–0.860)	> TR4	0.679 (0.540–0.797)	0.837 (0.787–0.880)	0.469 (0.360–0.578)	0.925 (0.891–0.958)	1.497	0.134
Kwak TI-RADS^a	0.832 (0.787–0.872)	> 4b	0.732 (0.597–0.842)	0.814 (0.762–0.859)	0.456 (0.353–0.558)	0.935 (0.903–0.967)	-	-
ACR score^b	0.931 (0.904–0.953)	> 5	0.963 (0.925–0.985)	0.765 (0.709–0.815)	0.746(0.691–0.801)	0.967(0.942–0.991)	1.754	0.079	2.869	0.004
ACR TI-RADS^b	0.886 (0.853–0.914)	> TR4	0.857 (0.799–0.904)	0.837 (0.787–0.880)	0.790(0.735–0.846)	0.891(0.852–0.930)	0.701	0.483	2.235	0.025
Kwak TI-RADS^b	0.900 (0.876–0.925)	> 4b	0.921 (0.882–0.959)	0.814 (0.767–0.861)	0.780(0.726–0.835)	0.935(0.903–0.967)	-	-

Z and P depicted the results compared with Kwak TI-RADS
Z^* and P^* revealed the results of ACR score ^b and ACR TI-RADS ^b compared with ACR score ^a and ACR TI-RADS ^a
ACR American College of Radiology, TI-RADS Thyroid Imaging Report and Data System, PPV Positive predictive value, NPV Negative predictive value, MTC Medullary thyroid carcinoma, PTC Papillary thyroid carcinoma
^aDiagnostic performance of ACR score, ACR TI-RADS and Kwak TI-RADS for MTC compared with benign nodules
^bDiagnostic performance of ACR score, ACR TI-RADS and Kwak TI-RADS for PTC compared with benign nodules

ISSN: 1472-6823