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Table 4 Association between type 2 diabetes status and liver stiffness (kpa)

From: Association between type 2 diabetes status and prevalence of liver steatosis and fibrosis among adults aged ≥ 40 years

 

Model 1 β (95% CI, P)

Model 2 β (95% CI, P)

Model 3 β (95% CI, P)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

1.9 (1.4, 2.3) < 0.001

1.8 (1.4, 2.3) < 0.001

0.8 (0.2, 1.3) 0.006

Stratified by sex

Men (n = 1,328)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

1.9 (1.2, 2.7) < 0.001

2.0 (1.2, 2.8) < 0.001

0.9 (0.0, 1.8) 0.046

Women (n = 1,452)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

1.7 (1.2, 2.3) < 0.001

1.7 (1.1, 2.2) < 0.001

0.4 (-0.2, 1.1) 0.173

Stratified by age

40–59 age group (n = 1,240)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

2.6 (1.9, 3.3) < 0.001

2.5 (1.8, 3.3) < 0.001

1.0 (0.1, 1.8) 0.027

60–80 age group (n = 1,540)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

1.5 (0.9, 2.1) < 0.001

1.5 (0.9, 2.1) < 0.001

0.7 (-0.0, 1.4) 0.058

Stratified by race

Non-Hispanic White (n = 979)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

2.2 (1.3, 3.0) < 0.001

2.1 (1.3, 2.9) < 0.001

0.2 (-0.7, 1.2) 0.631

Non-Hispanic Black (n = 624)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

0.7 (-0.3, 1.8) 0.170

0.7 (-0.3, 1.8) 0.176

0.0 (-1.2, 1.2) 0.980

Mexican American (n = 362)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

2.1 (1.3, 2.8) < 0.001

1.8 (1.0, 2.7) < 0.001

0.7 (-0.2, 1.6) 0.108

Other race (n = 815)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

2.5 (1.6, 3.4) < 0.001

2.4 (1.5, 3.3) < 0.001

1.8 (0.8, 2.9) < 0.001

Stratified by body mass index (BMI)

BMI < 25 (kg/m2) (n = 632)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

0.9 (0.3, 1.5) 0.003

0.9 (0.2, 1.5) 0.006

0.5 (-0.2, 1.2) 0.130

BMI ≥ 25, < 30 (kg/m2) (n = 951)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

1.1 (0.4, 1.9) 0.004

0.7 (-0.1, 1.5) 0.076

0.6 (-0.4, 1.6) 0.226

BMI ≥ 30 (kg/m2) (n = 1,197)

Non- diabetes

Reference

Reference

Reference

Type 2 diabetes

2.0 (1.2, 2.8) < 0.001

2.0 (1.2, 2.8) < 0.001

1.0 (0.1, 1.9) 0.032

  1. Model 1: no covariates were adjusted
  2. Model 2: age, sex, race were adjusted
  3. Model 3: age, sex, race, educational level, body mass index, ratio of family income to poverty, moderate recreational activities, smoked at least 100 cigarettes in life, blood urea nitrogen, total cholesterol, serum uric acid, alkaline phosphatase, alanine amino transferase, aspartic acid transferase, Gamma-glutamyl transpeptidase, and serum glucose were adjusted
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BMC Endocrine Disorders

ISSN: 1472-6823

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