Characteristics | Crude model | Adjusted model 1 | Adjusted model 2 | Adjusted model 3 | Adjusted model 4 |
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OR (95%CI)a | OR(95%CI)b | OR (95%CI)c | OR(95%CI)d | OR(95%CI)e |
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ALT |
 Normal ALT | 1 | 1 | 1 | 1 | 1 |
 Elevated ALT | 1.45(1.24–1.68) | 2.19(1.85–2.60) | 1.97(1.66–2.33) | 1.96(1.64–2.33) | 1.81(1.51–2.17) |
AST |
 Normal AST | 1 | 1 | 1 | 1 | 1 |
 Elevated AST | 1.75(1.37–2.42) | 1.92(1.47–2.51) | 1.79(1.37–2.34) | 1.78(1.35–2.35) | 1.75(1.32–2.32) |
GGT |
 Normal GGT | 1 | 1 | 1 | 1 | 1 |
 Elevated GGT | 2.22(1.94–2.56) | 2.13(1.84–2.48) | 1.98(1.71–2.31) | 1.99(1.70–2.32) | 1.77(1.50–2.08) |
ALP |
 Normal ALP | 1 | 1 | 1 | 1 | 1 |
 Elevated ALP | 2.00(1.74–2.30) | 1.65(1.42–1.92) | 1.66(1.42–1.94) | 1.67(1.42–1.96) | 1.60(1.35–1.90) |
- a The baseline model is stratified on the levels of liver enzymes
- b The adjusted model 1 is adjusted for confounding variables including age (continuous variable), gender (male/ female), education years (continuous variable) and wealth status index
- C The adjusted model 2 has additional adjustment for confounding variables related to lifestyle (cigarette smoking, alcohol drinking and opium consumption), body mass index (continuous variable) and physical activity level (continuous variable)
- d The adjusted model 3 has additional adjustment for hypertension (yes/no), family history of diabetes (first-degree relatives) (yes/no) and family history of diabetes (second-degree relatives) (yes/no)
- e The adjusted model 4 has additional adjustment for cholesterol (continuous variable), triglycerides (continuous variable), LDL cholesterol (continuous variable), HDL cholesterol (continuous variable), use of hepatotoxic drugs (yes/no) and fatty liver (yes/no)