Table 1 Genotype distribution and allele frequencies of OCT-1 polymorphisms in responders and non-responders
Genotype | Responder (n = 25) | Non-responder (n = 16) | P-value |
|---|---|---|---|
OCT-1 (156 T > C) | |||
TT | 15 (60.0%) | 9 (56.0%) | > 0.05 |
TC | 10 (40.0%) | 7 (44.0%) | |
Alleles | |||
T | 40 (80%) | 25 (78.125%) | > 0.05 |
C | 10 (20%) | 7 (21.875%) | |
OCT-1 (181 C > T) | |||
CC | 25 (100%) | 6 (37.5%) | < 0.001 |
CT | 0 | 10 (62.5%) | |
Alleles | |||
C | 50 (100%) | 22 (68.75%) | < 0.001 |
T | 0 (0%) | 10 (31.25%) | |
OCT-1 (1201 G > A) | |||
GG | 25 (100%) | 12(75.0%) | < 0.05 |
GA | 0 | 4 (25%) | |
Alleles | |||
G | 50 (100%) | 28 (87.5%) | < 0.05 |
A | 0 (0%) | 4 (12.5%) | |
OCT-1 (1222A > G) | |||
AA | 0 | 2 (12.5%) | < 0.05 |
AG | 05 (20.0%) | 9 (56.25%) | |
GG | 20 (80.0%) | 5 (31.25%) | |
Alleles | |||
A | 5 (10%) | 13 (40.625%) | < 0.05 |
G | 45 (90%) | 19 (59.375%) | |