Table 2 Characteristics of the study participants according to MC4R rs17782313 genotypes

Demography and anthropometry

  Age (year)

37.23 ± 8.65

35.77 ± 8.03

0.14

0.10

  Height (cm)

161.90 ± 5.85

160.98 ± 5.81

0.19

0.04a

  Weight (kg)

81.06 ± 12.32

80.28 ± 12.48

0.60

0.91a

  BMI (kg/m2)

31.06 ± 4.66

30.78 ± 3.90

0.58

0.46a

  WC (cm)

99.16 ± 10.31

98.53 ± 9.81

0.60

0.67a

  WHR

0.93 ± 0.05

1.64 ± 8.00

0.27

0.49a

Body composition

  Fat percentage (%)

41.38 ± 5.56

41.40 ± 5.39

0.97

0.32a

  Fat mass (kg)

34.02 ± 8.99

33.68 ± 8.30

0.74

0.42a

  FFM (%)

47.27 ± 5.53

46.23 ± 5.57

0.11

0.16a

  Visceral fat (%)

16.42 ± 11.41

16.93 ± 17.32

0.76

0.63a

  TBW (%)

34.72 ± 4.06

33.98 ± 4.10

0.73

0.19a

  Trunk fat (%)

16.55 ± 3.77

16.47 ± 3.64

0.85

0.36a

  BMR (kcal/day)

1391.22 ± 119.50

1368.69 ± 120.51

0.11

0.16a

  BMR/KG

17.35 ± 1.74

17.29 ± 1.50

0.77

0.17a

Blood parameters

  Insulin( IU/mL )

1.24 ± 0.22

1.19 ± 0.24

0.11

0.06

  FBS (mg/dL)

87.94 ± 10.21

86.24 ± 8.46

0.16

0.46

  TC (mg/dL)

185.19 ± 34.12

184.83 ± 38.08

0.93

0.33

  TG (mg/dL)

127.89 ± 74.23

114.52 ± 64.32

0.13

0.31

  HDL-C (mg/dL)

46.35 ± 9.94

47.07 ± 11.98

0.60

0.37

  LDL-C (mg/dL)

95.81 ± 23.23

93.84 ± 25.24

0.52

0.95

  hs-CRP (mg/L)

4.27 ± 4.53

4.62 ± 4.85

0.56

0.17

Blood pressure

  SBP (mmHg)

112.16 ± 14.04

110.92 ± 13.78

0.46

0.28

  DBP (mmHg)

77.92 ± 9.59

77.49 ± 9.87

0.71

0.50

  Physical activity score

1238.64 ± 1892.47

1177.10 ± 2371.62

0.82

0.92

Smoking

0.24

0.20

  yes

15

6

9

  no

267

148

119

Marital status

0.92

0.73

  Married

219

120

99

  Single

54

29

25

  Divorced

8

5

3

Education level

0.11

0.10

  Illiterate

3

0

3

  ≤ Diploma

119

63

56

  University degree

160

91

69