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Table 1 List of excluded studies

From: Association between type 2 diabetes (T2D) and tooth loss: a systematic review and meta-analysis

S.NO.

Reference

Reasons for Exclusion

1

Sznajder N, Carraro JJ, Rugna S, Sereday M. Periodontal findings in diabetic and nondiabetic patients. Journal of Periodontology. 1978;49 (9):445–8.

impossibility to calculate the effect size

2

Emrich LJ, Shlossman M, Genco RJ. Periodontal disease in non-insulin-dependent diabetes mellitus. Journal of periodontology. 1991;62 (2):123–31.

impossibility to calculate the effect size

3

Oliver RC, Tervonen T. PERIODONTITIS AND TOOTH LOSS - COMPARING DIABETICS WITH THE GENERAL-POPULATION. Journal of the American Dental Association. 1993;124 (12):71–6.

impossibility to calculate the effect size

4

Hernandez R, Cedola N, Caride E, Pereyra E, Olivera E. Dental pathology in diabetic patients: Absence or loss of teeth. Diabetologia. 1997;40:2356-.

Did not satisfy the outcome criteria

5

Persson RE, Hollender LG, MacEntee MI, Wyatt CCL, Kiyak HA, Persson GR. Assessment of periodontal conditions and systemic disease in older subjects. Focus on diabetes mellitus. Journal of Clinical Periodontology. 2003;30 (3):207–13.

Did not explore the exposure

6

Čuković-Bagić I, Verzak Ž, Car N, Car A. Tooth loss among diabetic patients. Diabetologia Croatica. 2004;33 (1):23–7.

impossibility to calculate the effect size

7

Negishi J, Kawanami M, Terada Y, Matsuhashi C, Ogami E, Iwasaka K, et al. Effect of lifestyle on periodontal disease status in diabetic patients. Journal of the International Academy of Periodontology. 2004;6 (4):120–4.

Did not satisfy the outcome criteria

8

Hu XW, Li CQ, Huang YH, Li XL, Guo F, Li P, et al. Epidemiological survey of the oral diseases of diabetics in west city district in Daqing city. Chinese Journal of Clinical Rehabilitation. 2005;9 (3):28–9.

impossibility to calculate the effect size

9

Mansour AA, Abd-Al-Sada N. Periodontal disease among diabetics in Iraq. MedGenMed: Medscape general medicine. 2005;7 (3):2.

impossibility to calculate the effect size

10

Faggion CM, Petersilka G, Lange DE, Gerss J, Flemmig TF. Prognostic model for tooth survival in patients treated for periodontitis. Journal of Clinical Periodontology. 2007;34 (3):226–31.

Did not explore the exposure

11

Hao JM, Meng HX, Ji LN. The investigation of the periodontal status of type 2 diabetes mellitus families. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2007;42 (7):408–11

Did not satisfy the outcome criteria

12

Demmer R, Phd MPH, Jacobs D, Desvarieux M, Md PHD. Periodontal Disease and Incident Type 2 Diabetes: Results from the First National Health and Nutrition Examination Survey and its Epidemiologic Follow-Up Study. Diabetes Care. 2008;31 (7):1373–9.

Did not satisfy the outcome criteria

13

Leung WK, Shing Chung S, Chu FC, Wong KW, Jin LJ, Sham AS, et al. Oral Health Status of Low-income, Middle-aged to Elderly Hong Kong Chinese with Type 2 Diabetes Mellitus. Oral Health & Preventive Dentistry. 2008;6 (2):105–18.

Did not satisfy the outcome criteria

14

Loe H. The relationship between diabetes and oral health among Australian adults. Australian Dental Journal. 2008;53 (1):93–6.

Did not satisfy the outcome criteria

15

Novak MJ, Potter RM, Blodgett J, Ebersole JL. Periodontal disease in Hispanic Americans with type 2 diabetes. Journal of periodontology. 2008;79 (4):629–36.

Did not satisfy the outcome criteria

16

Patino Marin N, Loyola Rodriguez JP, Medina Solis CE, Pontigo Loyola AP, Reyes Macias JF, Ortega Rosado JC, et al. Caries, periodontal disease and tooth loss in patients with diabetes mellitus types 1 and 2. Acta odontologica latinoamericana: AOL. 2008;21 (2):127–33.

impossibility to calculate the effect size

17

Tanwir F, Altamash M, Gustafsson A. Effect of diabetes on periodontal status of a population with poor oral health. Acta Odontologica Scandinavica. 2009;67 (3):129–33.

Did not satisfy the outcome criteria

18

Silva AM, Vargas AMD, Ferreira E, de Abreu MHNG. Periodontitis in individuals with diabetes treated in the public health system of Belo Horizonte, Brazil. Revista Brasileira de Epidemiologia. 2010;13 (1):118–25.

impossibility to calculate the effect size

19

Stojanovic N, Krunic J, Cicmil S, Vukotic O. Oral Health Status in Patients with Diabetes Mellitus Type 2 in Relation to Metabolic Control of the Disease. Srpski Arhiv Za Celokupno Lekarstvo. 2010;138 (7–8):420–4.

impossibility to calculate the effect size

20

Ueno M, Takeuchi S, Oshiro A, Shinada K, Ohara S, Kawaguchi Y. Association between diabetes mellitus and oral health status in Japanese adults. International journal of oral science. 2010;2 (2):82–9.

Did not satisfy the outcome criteria

21

Kanjirath PP, Kim SE, Rohr Inglehart M. Diabetes and oral health: the importance of oral health-related behavior. Journal of dental hygiene: JDH / American Dental Hygienists’ Association. 2011;85 (4):264–72.

Did not satisfy the study settings

22

Progression of periodontitis in a sample of regular and irregular compliers under maintenance therapy: a 3-year follow-up study

Did not explore the exposure

23

Bajaj S, Prasad S, Gupta A, Singh VB. Oral manifestations in type-2 diabetes and related complications. Indian journal of endocrinology and metabolism. 2012;16 (5):777–9.

Did not satisfy the outcome criteria

24

Botero JE, Yepes FL, Roldán N, Castrillón CA, Hincapie JP, Ochoa SP, et al. Tooth and periodontal clinical attachment loss are associated with hyperglycemia in patients with diabetes. Journal of Periodontology. 2012;83 (10):1245–50

impossibility to calculate the effect size

25

Costa FO, Santuchi CC, Lages EJP, Cota LOM, Cortelli SC, Cortelli JR, et al. Prospective study in periodontal maintenance therapy: comparative analysis between academic and private practices. Journal of periodontology. 2012;83 (3):301–11.

Did not satisfy the study settings

26

Demmer R, Holtfreter B, Desvarieux M, Jacobs D, Kerner W, Nauck M, et al. The Influence of Type 1 and Type 2 Diabetes on Periodontal Disease Progression: Prospective results from the Study of Health in Pomerania (SHIP). Diabetes Care. 2012;35 (10):2036–42.

Did not satisfy the outcome criteria

27

Ochoa SP, Ospina CA, Colorado KJ, Montoya YP, Saldarriaga AF, Miranda Galvis M, et al. [Periodontal condition and tooth loss in diabetic patients]. Biomedica: revista del Instituto Nacional de Salud. 2012;32 (1):52–9.

Did not satisfy the study settings

28

Pei P, Miao L, Zhang M, Zhang ST, Chen YJ. Epidemiological research on factors related to tooth loss of aged population. Chinese Journal of Conservative Dentistry/Yati Yasui Yazhoubingxue Zazhi. 2012;22 (5):292–4.

Did not explore the exposure

29

Batty GD, Li Q, Huxley R, Zoungas S, Taylor BA, Neal B, et al. Oral disease in relation to future risk of dementia and cognitive decline: prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. European psychiatry: the journal of the Association of European Psychiatrists. 2013;28 (1):49–52.

Did not satisfy for both

exposure and outcome

30

Huang DL, Chan KCG, Young BA. Poor Oral Health and Quality of Life in Older U.S. Adults with Diabetes Mellitus. Journal of the American Geriatrics Society. 2013;61 (10):1782–8.

Did not satisfy the outcome criteria

31

Kim EK, Lee SG, Choi YH, Won KC, Moon JS, Merchant AT, et al. Association between diabetes-related factors and clinical periodontal parameters in type-2 diabetes mellitus. BMC Oral Health. 2013;13 (1).

Did not satisfy the outcome criteria

32

Al-Khabbaz AK. Type 2 diabetes mellitus and periodontal disease severity. Oral Health and Preventive Dentistry. 2014;12 (1):77–82.

Did not satisfy the outcome criteria

33

Amiri AA, Maboudi A, Bahar A, Farokhfar A, Daneshvar F, Khoshgoeian HR, et al. Relationship between type 2 diabetic retinopathy and periodontal disease in Iranian adults. North American Journal of Medical Sciences. 2014;6 (3):139–44.

Did not satisfy the outcome criteria

34

Azogui-Lévy S, Rochereau T. [Dental health and dental care according diabetic status; results from 2008 ESPS study]. Revue d’epidemiologie et de sante publique. 2014;62 (6):329–37.

Did not satisfy the study settings

35

Cai M, Liang R, Xu Y, Peng H, Wu W. Correlation between tooth loss and chronic disease of elders in Hebei province. Zhengzhou Daxue Xuebao (Yixue Ban) - Journal of Zhengzhou University Medical sciences. 2014;49 (4):577–9.

Did not explore the exposure

36

Passeri CR, Freitas AR, Aznar FD, Caracik J, Peres AS, Peres SCS. IMPACT OF TOOTH LOSS ON QUALITY OF LIFE IN DIABETIC AND NON-DIABETIC MORBIDLY OBESE PATIENTS. Obesity Surgery. 2014;24 (8):1204–5.

Did not explore the exposure

37

Luo H, Pan W, Sloan F, Feinglos M, Wu B. Forty-year trends in tooth loss among american adults with and without diabetes mellitus: An age-period-cohort analysis. Preventing Chronic Disease. 2015;12 (12).

impossibility to calculate the effect size

38

Juncar RI, Juncar M, Popa AR. Oral disease in diabetic patients - A pilot study. Romanian Journal of Diabetes, Nutrition and Metabolic Diseases. 2016;23 (3):247–54.

Did not satisfy the study settings

39

Lo TE, Lagaya-Estrada MC, Jimeno C, Jasul G, Jr. Clinical utility of self-reported oral health measures for predicting periodontitis among adult filipinos with type 2 diabetes mellitus. Journal of the ASEAN Federation of Endocrine Societies. 2016;31 (1):10–7.

Did not satisfy the outcome criteria

40

Padmalatha GV, Bavle RM, Satyakiran GVV, Paremala K, Sudhakara M, Makarla S. Quantification of Porphyromonas gingivalis in chronic periodontitis patients associated with diabetes mellitus using real-time polymerase chain reaction. Journal of oral and maxillofacial pathology: JOMFP. 2016;20 (3):413–8.

Did not satisfy the study settings

41

Ramli NIN, Alkaff SNIASMN, Faisal GG, Bayati LHA. Diabetes mellitus; its impact on periodontal health and dental caries. Journal of International Dental and Medical Research. 2016;9 (3):164–8.

Did not satisfy the study settings

42

Schulze A, Busse M. Gender Differences in Periodontal Status and Oral Hygiene of Non-Diabetic and Type 2 Diabetic Patients. Open Dentistry Journal. 2016;10:287–97.

Did not satisfy the outcome criteria

43

Thaper S, Thaper T, Vishnu Priya V, Thaper R, Thaper R. Prevalence of periodontitis in diabetic and non-diabetic patients. Asian Journal of Pharmaceutical and Clinical Research. 2016;9 (1):308–10.

Did not satisfy the outcome criteria

44

Yang BT, Xu JL, He L, Meng HX, Xu L. Porphyromonas gingivalis FimA genotype distribution among periodontitis patients with type 2 diabetes. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2016;51 (1):20–4.

Did not satisfy the study settings

45

Alyasiry AM. Oral Hygiene For The Diabetes Mellitus And Osteoporosis Patients. Research Journal of Pharmaceutical Biological and Chemical Sciences. 2017;8 (3):783–91.

Did not satisfy the outcome criteria

46

Brignardello-Petersen R. Age, sex, diabetes mellitus, and endodontic treatment affect incidence of tooth loss after periodontal treatment. Journal of the American Dental Association. 2017;148 (4):e43.

impossibility to calculate the effect size

47

D’Aiuto F, Gable D, Syed Z, Allen Y, Wanyonyi KL, White S, et al. Evidence summary: The relationship between oral diseases and diabetes. British Dental Journal. 2017;222 (12):944–8.

Did not satisfy the study settings

48

Singh AK, Mishra R. A Prospective Study Establishing Correlation between Diabetes and Tooth Loss. Journal of Advanced Medical and Dental Sciences Research. 2017;5 (12):119A-23A.

impossibility to calculate the effect size

49

Song SJ, Han K, Lee SS, Park JB. Association between the number of natural teeth and diabetic retinopathy among type 2 diabetes mellitus: The Korea national health and nutrition examination survey. Medicine (United States). 2017;96 (47).

Did not explore the exposure

50

Wiener RCMADMDP, Shen CP, Findley PAD, Sambamoorthi UP, Tan XP. The association between diabetes mellitus, sugar-sweetened beverages, and tooth loss in adults: Evidence from 18 states. American Dental Association The Journal of the American Dental Association. 2017;148 (7):500.

impossibility to calculate the effect size

51

Ahmad B, Ahmad O, Afzal M. THE ETIOLOGY OF TOOTH LOSS AND RISK FACTORS CAUSING PERIODONTAL DISEASE. Indo American Journal of Pharmaceutical Sciences. 2018;5 (12):14009–14.

Did not explore the exposure

52

Maia FB, de Sousa ET, Sampaio FC, Freitas CH, Forte FD. Tooth loss in middle-aged adults with diabetes and hypertension: Social determinants, health perceptions, oral impact on daily performance (OIDP) and treatment need. Medicina oral, patologia oral y cirugia bucal. 2018;23 (2):e203-e10.

impossibility to calculate the effect size

53

Oliveira EJP, Roch VFB, Nogueira DA, Pereira AA. Quality of life and oral health among hypertensive and diabetic people in a Brazilian Southeastern city. Ciencia e Saude Coletiva. 2018;23 (3):763–72.

Did not satisfy the outcome criteria

54

Trentin MS, De Carli JP, Ferreira MD, Gambin DJ, da Silva SO, Lisboa H. PREVALENCE AND SEVERITY OF PERIODONTAL DISEASE IN TYPE 2 DIABETES MELLITUS PATIENTS: A CROSS-SECTIONAL STUDY. Bioscience Journal. 2018;34 (4):1114–23.

Did not satisfy the study settings

55

Afolabi O, Adeniyi A, Sofola O, Ogbera A. Effect of glycemic control on periodontal disease and caries experience in diabetic patients: A pilot study. Journal of Interdisciplinary Dentistry. 2019;9 (3):99–107.

Did not satisfy the study settings

56

Glurich I, Acharya A. Updates from the Evidence Base Examining Association between Periodontal Disease and Type 2 Diabetes Mellitus: Current Status and Clinical Relevance. Current Diabetes Reports. 2019;19 (11).

Did not satisfy the study settings

57

Izuora K, Yousif A, Allenback G, Gewelber C, Neubauer M. Relationship between dental loss and health outcomes among hospitalized patients with and without diabetes. Journal of Investigative Medicine. 2019;67 (3):669–73.

impossibility to calculate the effect size

58

Khan SQ, Khabeer A, Al-Thobity AM, Benrashed MA, Alyousef NI, AlMaimouni Y. Correlation between diabetes mellitus and number of restored, carious lesions and missing teeth: A retrospective radiographic evaluation. Saudi Dental Journal. 2020.

impossibility to calculate the effect size

59

Furukawa T, Wakai K, Yamanouchi K, Oshida Y, Miyao M, Watanabe T, et al. Associations of periodontal damage and tooth loss with atherogenic factors among patients with type 2 diabetes mellitus. Intern Med. 2007;46 (17):1359–64.

Did not satisfy the study settings

60

Wu CZ, Yuan YH, Liu HH, Li SS, Zhang BW, Chen W, et al. Epidemiologic relationship between periodontitis and type 2 diabetes mellitus. BMC Oral Health. 2020;20 (1):204.

Did not satisfy the outcome criteria

61

Panezai J, Altamash M, Engstrm PE, Larsson A. Association of glycated proteins with inflammatory proteins and periodontal disease parameters. Journal of Diabetes Research. 2020;2020.

Did not satisfy the outcome criteria

62

Ohtani M, Nishimura T. The preventive and therapeutic application of garlic and other plant ingredients in the treatment of periodontal diseases. Experimental and Therapeutic Medicine. 2020;19 (2):1507–10.

Did not satisfy the study settings

63

Yuan-Jung H, Kun-Der L, Jen-Hao C, Lee M-Y, Ying-Chu L, Feng-Chieh Y, et al. Periodontal Treatment Experience Associated with Oral Health-Related Quality of Life in Patients with Poor Glycemic Control in Type 2 Diabetes: A Case-Control Study. International Journal of Environmental Research and Public Health. 2019;16 (20).

Did not satisfy the study settings

64

Teufer B, Sommer I, Nussbaumer-Streit B, Titscher V, Bruckmann C, Klerings I, et al. Screening for periodontal diseases by non-dental health professionals: a protocol for a systematic review and overview of reviews. Systematic reviews. 2019;8 (1):61.

Did not satisfy the study settings

65

Salmeron D, Garcia FG, Pons-Fuster E, Perez-Sayans M, Lorenzo-Pouso AI, Lopez-Jornet P. Screening for prediabetes and risk of periodontal disease. Diabetes & Metabolic Syndrome-Clinical Research & Reviews. 2019;13 (2):1661–6.

Did not satisfy for both

exposure and outcome

66

Pockpa ZAD, Struillou X, Kone D, Mobio GS, Soueidan A, Badran Z. Periodontal Diseases and Age-Related Macular Degeneration: Is There a Link? A Review. The Permanente journal. 2019;23.

Did not satisfy the study settings

67

Kim YT, Choi JK, Kim DH, Jeong SN, Lee JH. Association between health status and tooth loss in Korean adults: Longitudinal results from the National Health Insurance Service-Health Examinee Cohort, 2002–2015. Journal of Periodontal and Implant Science. 2019;49 (3):158–70.

Did not explore the exposure

68

Jin DSS, Liao YT, He L, Meng HX, Li P. [Study on periodontal status of patients with pre-diabetes]. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2019;54 (3):157–63.

Did not satisfy the study settings

69

Andriankaja OM, Joshipura K. Potential association between prediabetic conditions and gingival and/or periodontal inflammation. Journal of Diabetes Investigation. 2014;5 (1):108–14.

Did not satisfy for both

exposure and outcome

70

Sima C, Glogauer M. Diabetes mellitus and periodontal diseases. Current Diabetes Reports. 2013;13 (3):445–52.

impossibility to calculate the effect size

71

Leite RS, Marlow NM, Fernandes JK. Oral Health and Type 2 Diabetes. American Journal of the Medical Sciences. 2013;345 (4):271–3.

Did not satisfy the study settings

72

Jiang X, Zhu Y, Liu Z, Tian Z, Zhu S. Association between diabetes and dental implant complications: a systematic review and meta-analysis. Acta Odontologica Scandinavica. 2021;79 (1):9–18.

Did not satisfy the study settings

73

Raju K, Taylor GW, Tahir P, Hyde SS. Association of tooth loss with morbidity and mortality by diabetes status in older adults: a systematic review. Bmc Endocrine Disorders. 2021;21 (1).

Did not satisfy the study settings

74

Carvalho R, Botelho J, Machado V, Mascarenhas P, Alcoforado G, Mendes JJ, et al. Predictors of tooth loss during long-term periodontal maintenance: An updated systematic review. Journal of clinical periodontology. 2021;48 (8):1019–36.

Did not satisfy the study settings

75

Weijdijk LPM, Ziukaite L, Van der Weijden GA, Bakker EWP, Slot DE. The risk of tooth loss in patients with diabetes: A systematic review and meta-analysis. International journal of dental hygiene. 2022;20 (1):145–66.

Did not satisfy the study settings

76

Liljestrand JM, Salminen A, Lahdentausta L, Paju S, Mäntylä P, Buhlin K, et al. Association between dental factors and mortality. 2021;54 (5):672–81.

Did not satisfy for both

exposure and outcome

77

Jacob L, Shin JI, Oh H, Lopez-Sanchez GF, Smith L, Haro JM, et al. Association between diabetes and edentulism and their joint effects on health status in 40 low and middle-income countries. Bmj Open Diabetes Research & Care. 2021;9 (1).

Did not satisfy the outcome criteria

78

Altun E, Walther C, Borof K, Petersen E, Lieske B, Kasapoudis D, et al. Association between dietary pattern and periodontitis—a cross-sectional study. Nutrients. 2021;13 (11).

Did not explore the exposure

79

Chatzopoulos GS, Cisneros A, Sanchez M, Wolff LF. Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study. Antibiotics (Basel, Switzerland). 2021;10 (4).

Did not satisfy the study settings

80

Menon GR, Malaiappan S, Kumar K. Association between right upper molar involvement and diabetes mellitus in subjects with chronic periodontitis. International Journal of Dentistry and Oral Science. 2021;8 (6):2879–84.

Did not satisfy the outcome criteria

81

Tegelberg P, Tervonen T, Knuuttila M, Jokelainen J, Keinänen-Kiukaanniemi S, Auvinen J, et al. Association of hyperglycaemia with periodontal status: Results of the Northern Finland Birth Cohort 1966 study. Journal of clinical periodontology. 2021;48 (1):24–36.

Did not satisfy the outcome criteria

82

Barma MD, Raj SS, Jayashri P. Clinical Periodontal Parameters Associated with Diabetes Mellitus in Patients Attending a Private Dental Hospital in Chennai. Bioscience Biotechnology Research Communications. 2021;14 (10):83–9.

Did not satisfy the outcome criteria

83

Song TJ, Chang Y, Jeon J, Kim J. Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. 2021;16 (6):e0253769.

Did not satisfy the outcome criteria

84

Al-Zahrani MS, Alhassani AA, Zawawi KH. Tooth loss as a potential risk factor for deficient sleep: an analysis of a nationally representative sample of adults in the USA. Journal of public health dentistry. 2021;25 (2):1101–7.

Did not explore the exposure

85

Madi M, Abuohashish HM, Attia D, AlQahtani N, Alrayes N, Pavlic V, et al. Association between Periodontal Disease and Comorbidities in Saudi’s Eastern Province. Biomed Research International. 2021;2021.

Did not satisfy the outcome criteria

86

Yu YH, Cheung WS, Steffensen B, Miller DR. Number of teeth is associated with all-cause and disease-specific mortality. BMC oral health. 2021;21 (1).

Did not explore the exposure

87

Yang LX, Ge Q, Ye ZT, Wang LJ, Wang LP, Mashrah MA, et al. Sulfonylureas for Treatment of Periodontitis-Diabetes Comorbidity-Related Complications: Killing Two Birds With One Stone. Frontiers in Pharmacology. 2021;12.

impossibility to calculate the effect size

88

Tae-Jin S, Chang Y, Jeon J, Kim J. Oral health and longitudinal changes in fasting glucose levels: A nationwide cohort study. PloS one. 2021;16 (6).

impossibility to calculate the effect size

89

Sunakawa Y, Tsugayasu H, Watanabe Y, Matsushita T, Ohara Y, Iwasaki M, et al. Relationship between weight loss and regular dental management of older adults residing in long-term care facilities: a 1-year multicenter longitudinal study. European Geriatric Medicine. 2021.

Did not satisfy for both

exposure and outcome

90

Stødle IH, Verket A, Høvik H, Sen A, Koldsland OC. Prevalence of periodontitis based on the 2017 classification in a Norwegian population: The HUNT study. Journal of clinical periodontology. 2021;48 (9):1189–99.

Did not explore the exposure

91

Song TJ, Jeon J, Kim J. Cardiovascular risks of periodontitis and oral hygiene indicators in patients with diabetes mellitus. Diabetes and Metabolism. 2021;47 (6).

Did not satisfy the outcome criteria

92

Shi S, Ding F, Liu X, Wang L, Wang X, Zhang S, et al. Clinical and radiographic variables related to implants with simultaneous grafts among type 2 diabetic patients treated with different hypoglycemic medications: a retrospective study. BMC oral health. 2021;21 (1):214.

Did not satisfy the outcome criteria

93

Shang R, Gao L. Impact of hyperglycemia on the rate of implant failure and peri-implant parameters in patients with type 2 diabetes mellitus: Systematic review and meta-analysis. Journal of the American Dental Association. 2021;152 (3):189–201.e1.

Did not satisfy the study settings

94

Rodakowska E, Jamiolkowski J, Baginska J, Kaminska I, Gabiec K, Stachurska Z, et al. Oral Health–Related Quality of Life and Missing Teeth in an Adult Population: A Cross-Sectional Study from Poland. International journal of environmental research and public health. 2022;19 (3):1626.

Did not explore the exposure

95

Reham Khaled Abou El F, Mona Ahmed Abdel F, Muhammad Ahmed H, Wassel MO, Amira Saad B, Huda Ahmed Amin E, et al. Periodontal diseases and potential risk factors in Egyptian adult population—Results from a national cross-sectional study. PloS one. 2021;16 (11).

Did not satisfy the outcome criteria

96

Raedel M, Noack B, Priess HW, Bohm S, Walter MH. Massive data analyses show negative impact of type 1 and 2 diabetes on the outcome of periodontal treatment. Clinical oral investigations. 2021;25 (4):2037–43.

Did not satisfy the outcome criteria

97

Patel J, Kulkarni S, Doshi D, Poddar P, Srilatha A, Reddy KS. Periodontal disease among non-diabetic coronary heart disease patients. A case-control study. Acta Biomedica. 2021;92 (1):1–11.

Did not satisfy for both

exposure and outcome

98

Mukkavilli M, Kulkarni S, Doshi D, Reddy S, Adepu S, Reddy S. Oral health status and self- assessment of oral health risk factors among South Indian diabetic patients: Official Publication of Indian Society for Dental Research. Indian Journal of Dental Research. 2021;32 (2):140–6.

Did not explore the exposure

99

Luo H, Wu B, Kamer AR, Adhikari S, Sloan F, Plassman BL, et al. Oral Health, Diabetes, and Inflammation: Effects of Oral Hygiene Behaviour. International Dental Journal. 2021.

Did not satisfy the outcome criteria