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Table 3 Multivariate regression analysis on HbA1c in men and women

From: The relationship between sex hormones and glycated hemoglobin in a non-diabetic middle-aged and elderly population

HbA1c

Multivariate model

standardized β

t

P

Men (n = 601)

 hemoglobin

− 0.162

− 3.925

<  0.001

 FPG

0.165

4.166

<  0.001

 E2

0.134

3.384

0.001

 BMI

0.136

3.415

0.001

 age

0.115

2.868

0.004

 LDL-c

0.087

2.200

0.028

Women (n = 808)

 SHBG

−0.161

−3.858

<  0.001

 age

0.200

3.505

<  0.001

 FPG

0.129

3.277

0.001

 SBP

0.114

2.354

0.019

  1. For men, multivariate model included age, BMI, SBP, DBP, FPG, 2hPG, HOMA-IR, TC, TG, HDL-c, LDL-c, CRP, hemoglobin and E2. For women, multivariate model included age, years since menopause, BMI, SBP, DBP, FPG, 2hPG, HOMA-IR, TC, TG, HDL-c, LDL-c, CRP, hemoglobin and SHBG
  2. Abbreviation: HbA 1c Glycated haemoglobin A1c, E 2 Estradiol, BMI Body mass index, SHBG Sex hormone-binding globulin, SBP Systolic blood pressure, DBP Diastolic blood pressure, FPG Fasting plasma glucose, 2hPG 2-h plasma glucose, HOMA-IR Homeostasis model assessment-insulin resistance index, TC Total cholesterol, TG Triglyceride, HDL-c High-density lipoprotein cholesterol, LDL-c Low-density lipoprotein cholesterol, CRP C-reactive protein