Skip to main content

Table 5 Risk factors of positive thyroid autoantibodies, positive TPO-Ab and positive Tg-Ab

From: Obesity is associated with subclinical hypothyroidism in the presence of thyroid autoantibodies: a cross-sectional study

 

Model 1

Model 2

Model 3

OR(95%CI)

P

OR(95%CI)

P

OR(95%CI)

P

Univariate logistic analysis

 Sex

3.069 (2.424,3.887)

< 0.001

2.402 (1.815,3.178)

< 0.001

3.845 (2.917,5.068)

< 0.001

 Age

0.950 (0.700,1.289)

0.740

1.038 (0.721,1.492)

0.843

0.853 (0.604,1.204)

0.365

 Smoking

0.420 (0.307,0.573)

< 0.001

0.581 (0.408,0.827)

0.003

0.293 (0.198,0.434)

< 0.001

 Obesity

1.198 (0.880,1.630)

0.251

1.215 (0.839,1.759)

0.304

1.391 (1.006,1.922)

0.046

 Diabetes Mellitus

1.237 (0.777,1.970)

0.370

0.889 (0.534,1.481)

0.652

1.374 (0.808,2.338)

0.241

 Hypertension

1.016 (0.804,1.285)

0.892

0.950 (0,715,1.261)

0.722

1.013 (0.784,1.309)

0.921

 Urinary iodine concentration

1.000 (0.999,1.001)

0.955

1.000 (0.999,1.001)

0.679

1.000 (0.999,1.001)

0.845

Multiple logistic analysis

 Sex

–

–

–

–

3.284 (2.368,4.553)

< 0.001

 Age

–

–

–

–

0.845 (0.594,1.203)

0.350

 Smoking

–

–

–

–

0.671 (0.420,1.070)

0.094

 Obesity

–

–

–

–

1.504 (1.077,2.101)

0.017

  1. Univariate logistic regression, when adjusted for sex (male and female), age (<65y and ≥ 65y), smoking status (non-smoking and smoking), obesity (no and yes), diabetes mellitus (no and yes), hypertension (no and yes), urinary iodine concentration (continuous variable) was used for identify the associated risk factors for positive thyroid autoantibodies (model 1), positive TPO-Ab (model 2) and Tg-Ab (model 3), respectively. Factors that differed in the univariate logistic analysis were further analysed in the multiple logistic analysis. P < 0.05 was considered significant
  2. TPO-Ab Thyroid peroxidase antibody, Tg-Ab Thyroglobulin antibody
Back to article page