Obesity is associated with subclinical hypothyroidism in the presence of thyroid autoantibodies: a cross-sectional study

Table 4 Correlations of body mass index and thyroid stimulating hormone among total subjects, subjects with positive thyroid autoantibodies, and subjects with negative autoantibodies

	Total subjects		Subjects with positive thyroid autoantibodies		Subjects with negative autoantibodies
	r(95%CI)	P	r(95%CI)	P	r(95%CI)	P
Sex	−0.201(− 0.556,0.153)	0.266	− 0.342(−2.556,1.871)	0.761	− 0.146(− 0.293, 0.002)	0.053
Age	− 0.009(− 0.018, 0.001),	0.072	− 0.024(− 0.078,0.030)	0.379	−0.005(−.009,0.000)	0.016
Smoking	−0.559(− 0.983,-0.134)	0.010	−1.736(−4.693, 1.221)	0.249	−0.415(− 0.588,-0.241)	< 0.001
BMI	0.063 (0.022,0.104)	0.003	0.211 (0.007, 0.415)	0.043	0.024 (0.006,0.042)	0.008
Urinary iodine concentration	0.000 (0.000,0.001)	0.071	−0.001(−0.005,0.003)	0.578	0.000 (0.000,0.001)	0.049
TPO-Ab	1.300 (0.747, 1.853)	< 0.001	–	–	–	–
Tg-Ab	0.740 (0.237,1.243)	0.004	–	–	–	–

Multiple liner regression, when adjusted for sex (male and female), age (continuous variable), smoking status (non-smoking and smoking), BMI (continuous variable), urinary iodine concentration (continuous variable), TPO-Ab (negativity and positivity) and Tg-Ab (negativity and positivity) was used for identify the correlation of TSH among the total subjects; Multiple liner regression, when adjusted for sex (male and female), age (continuous variable), smoking status (non-smoking and smoking), BMI (continuous variable) and urinary iodine concentration (continuous variable) was used for identify the correlation of TSH among subjects with positive thyroid autoantibodies, and subjects with negative autoantibodies, respectively. P < 0.05 was considered significant
BMI Body mass index, TPO-Ab Thyroid peroxidase antibody, Tg-Ab thyroglobulin antibody

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