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Table 1 General characteristics of obese and nonobese subjects

From: Obesity is associated with subclinical hypothyroidism in the presence of thyroid autoantibodies: a cross-sectional study

 

Obese subjects (n = 289)

Nonobese subjects (n = 2216)

P

Age(y)

49.07 ± 13.97

45.28 ± 15.89

< 0.001

Age category [n(%)]

  

0.198

  < 65y

243 (84.08%)

1926 (86.91%)

 

  ≥ 65y

46%(15.92%)

290 (13.09%)

 

Sex [n(%)]

  

0.321

 Male

135 (46.71%)

971 (43.81%)

 

 Female

154 (53.29%)

1245 (56.18%)

 

BMI (kg/m2)

30.39 ± 2.30

22.66 ± 2.77

< 0.001

Waist circumference (cm)

97.18 ± 7.13

80.18 ± 9.31

< 0.001

Hip circumference (cm)

104.85 ± 0.59

93.32 ± 0.13

< 0.001

Percentage of body fat(%)

34.31 ± 6.02

26.71 ± 6.78

< 0.001

Smoking status [n(%)]

  

0.006

 No

209 (72.32%)

1765 (79.65%)

 

 Yes

80 (27.68%)

451 (20.35%)

 

DM [n(%)]

  

0.035

 No

263 (91.00%)

2090 (94.31%)

 

 Yes

26 (9.00%)

126 (5.69%)

 

Hypertension [n(%)]

  

< 0.001

 No

249 (86.16%)

2067 (93.28%)

 

 Yes

40 (13.84%)

149 (6.72%)

 

Urinary iodine concentration (μg/L)

137.00 (94.35–194.50)

128.00 (87.05–181.38)

0.028

Subclinical hypothyroidism [n(%)]

  

0.045

 Yes

27 (9.34%)

138 (6.23%)

 

 No

262 (90.66%)

2078 (93.77%)

 

Positive TPO-Ab and/or Tg-Ab [n(%)]

  

0.250

 Yes

58 (20.07%)

384 (17.33%)

 

 No

231 (79.93%)

1832 (82.67%)

 

Positive TPO-Ab and Tg-Ab [n(%)]

  

0.032

 Yes

31 (10.73%)

157 (7.08%)

 

 No

258 (89.27%)

2059 (92.92%)

 

Positive Tg-Ab [n(%)]

  

0.045

 Yes

52 (17.99%)

302 (13.63%)

 

 No

237 (82.01%)

1914 (86.37%)

 

Positive TPO-Ab [n(%)]

  

0.303

 Yes

37 (12.80%)

239 (10.79%)

 

 No

252 (87.20%)

1977 (89.21%)

 

Serum TSH level (mIU/L)

1.82 (1.25,2.64)

1.97 (1.24,2.70)

0.261

  1. Age, BMI, waist circumference and percentage of body fat were expressed as the means±standard deviations; urinary iodine concentration and serum TSH level was expressed as medians with interquartile ranges; age category, sex, smoking status, DM, hypertension, subclinical hypothyroidism, thyroid autoantibodies, Tg-Ab and TPO-Ab were presented as n (%)
  2. The t test was used for age, BMI, waist circumference and percentage of body fat; the Mann–Whitney U test was adopted for urinary iodine concentration and serum TSH level; the χ2 test was used for age category, sex, smoking status, DM, hypertension, subclinical hypothyroidism, thyroid autoantibodies, Tg-Ab and TPO-Ab. P < 0.05 was considered significant
  3. BMI Body mass index, DM Diabetes mellitus, TPO-Ab Thyroid peroxidase antibody, Tg-Ab Thyroglobulin antibody, TSH Thyroid stimulating hormone