Table 1 Baseline laboratory tests to confirm MEN1 in the index patient and family members
From: Distinct clinical phenotypes in a family with a novel truncating MEN1 frameshift mutation
Laboratory tests (normal range) | Index patient | Father | Brother | Sister |
|---|---|---|---|---|
Calcium mmol/l (2.09 – 2.54) | 2.8 | 3.2 | 2.9 | 2.4 |
Phosphate mmol/l (2.6 – 4.5) | 2.2 | 2.2 | 1.6 | 2.4 |
Albumine g/dl (3.5 – 5.2) | 4.8 | 4.4 | 4.8 | 4.3 |
PTH pg/ml (15 – 65) | 117.0 | 258.0 | 89.0 | 76.0 |
Gastrin pg/ml (13 – 115) | 59.0 | 62.0 | 10.0 | 18.0 |
Chromogranin A U/l (< 35) | 12.2 | 19.0 | 11.0 | 14.0 |
Prolactin mg/dl (4.6 – 21.4) | 93.0 | 12.0 | 18.5 | 50.4 |
Fasting blood glucose mmol/l (82 – 115) | 2.7 | n/d | n/d | n/d |
Insulin µIU/ml (2.6 – 24.9) | 27.0 | 57.0 | 10.0 | n/d |
C-peptide ng/ml (1.1 – 4.4) | 3.3 | 7.7 | n/d | n/d |
IGF-1 ng/ml (78 – 220) | 206.0 | 167.0 | 179.0 | 135 |
25-OH Vitamin D3 ng/ml (10 – 25) | 13.0 | 4,1 | 14.0 | < 4.0 |