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Fig. 3 | BMC Endocrine Disorders

Fig. 3

From: A case of atypical reninoma with mild hypertension and normal plasma renin activity but elevated plasma renin concentration

Fig. 3

A proposed diagnostic flowchart for reninoma diagnosis. 1 Features indicative of secondary hypertension include young age at onset (less than 30), sudden onset of hypertension, uncontrolled refractory hypertension, malignant hypertension, and hypokalaemia. 2 Features of renal lesions indicative of reninoma include tumour occurring in adolescence or early adulthood, in female, small (2–3 cm) solitary subcapsular mass, hypo- to isodense to the renal parenchyma, hypovascular in the arterial phase, and delayed enhancement on CT scan, or T1 hypointense, T2 hypointense, and hypovascular after contrast administration on MRI. 3 If normal plasma renin activity, verify by measuring direct renin concentration. PRC, plasma renin concentration; PRA, plasma renin activity; SRVS, selective renal vein sampling

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