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Table 1 Characteristics of the participants stratified

From: Circ_0000064 promotes high glucose-induced renal tubular epithelial cells injury to facilitate diabetic nephropathy progression through miR-532-3p/ROCK1 axis

Clinical parameter

normal

microalbuminuria

macroalbuminuria

Age (years)

51.6 ± 10.5

60.1 ± 11.8

65.9 ± 12.8

Duration of diabetes (years)

5 (1, 8)

9 (4, 14)

12 (9, 22)

BMI (kg/m2)

24.1 (22.4, 25.9)

24.8 (22.5, 27.1)

25.1 (23.1, 26.1)

SBP (mmHg)

133 ± 19

147 ± 20

151 ± 22

DBP (mmHg)

82 ± 12

86 ± 13

84 ± 11

PP (mmHg)

49 (42, 58)

55 (44, 66)

66 (48, 78)

FPG (mmol/L)

7.68 (6.32, 9.61)

8.66 (6.32, 10.25)

8.96 (6.65, 10.95)

eGFR (ml/min/1.73m2)

101.2 (92.3, 108.5)

89.2 (80.5, 96.8)

52.3 (41.5, 59.6)

UACR (mg/g)

8 (5, 13)

99 (62, 149)

411 (198, 771)

TG (mmol/L)

1.55 (1.01, 2.15)

1.75 (1.98, 2.36)

1.76 (1.89, 2.59)

TC (mmol/L)

4.81 (4.01, 5.63)

5.12 (4.65, 5.96)

5.01 (4.33, 5.75)

  1. BMI body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, PP Pulse pressure, FPG Fasting plasma glucose, eGFR Estimated glomerular filtration rate, UACR Urinary albumin-to-creatinine ratio, TG Triglycerides, TC Total cholesterol