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Fig. 4 | BMC Endocrine Disorders

Fig. 4

From: Circ_0000064 promotes high glucose-induced renal tubular epithelial cells injury to facilitate diabetic nephropathy progression through miR-532-3p/ROCK1 axis

Fig. 4

MiR-532-3p could be sponged by circ_0000064. A The binding sites and mutant sites between circ_0000064 and miR-532-3p were shown. B The expression of miR-532-3p was detected by qRT-PCR in the serum of DN patients with microalbuminuria or macroalbuminuria and normal healthy volunteers. C QRT-PCR was used to measure the miR-532-3p expression in HK-2 cells under HG, NG or mannitol condition. Dual-luciferase reporter assay (D) and RNA pull-down assay (E) were used to assess the interaction between circ_0000064 and miR-532-3p. ***P < 0.001

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BMC Endocrine Disorders

ISSN: 1472-6823

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