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Fig. 1 | BMC Endocrine Disorders

Fig. 1

From: Circ_0000064 promotes high glucose-induced renal tubular epithelial cells injury to facilitate diabetic nephropathy progression through miR-532-3p/ROCK1 axis

Fig. 1

HG could induce HK-2 cells injury. HK-2 cells were cultured under HG, NG or mannitol condition. A-B Cell oxidative stress was assessed by determining the levels of SOD and MDA. CCK8 assay (C) and EDU assay (D) were performed to assess cell proliferation. E-G The protein expression of PCNA and cyclin D1 was measured by WB analysis. H Cell apoptosis rate was evaluated by flow cytometry. I-K WB analysis was used to examine the protein expression of Bax and Bcl2. ***P < 0.001

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