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Table 1 Diagnoses of Growth Hormone Deficiency in adulthood according to AIFA Note#39, as reported to the RNAOC-web platform by the clinical specialist centres from January 1st 2011 to December 31st 2019

From: Somatropin therapy in italian adults with growth hormone deficiency

Adulthood diagnoses Subjects Males Females
  n. % n. % n. %
Hypopituitarism:
idiopathic, autoimmune hypophysitis, post-cranio-encephalic trauma, surgery or irradiation for sellar or parasellar tumors, empty sella, Sheehan syndrome
579 59.69 338 59.72 241 59.65
Hypopituitarism:
post total or partial hypophysectomy
383 39.48 223 39.40 160 39.60
Congenital GH deficiency with demonstrated genetic defect 3 0.31 1 0.18 2 0.50
Not included in Note#39 5 0.52 4 0.70 1 0.25
Total 970   566   404