Associations between thyroid function and gestational diabetes mellitus in Chinese pregnant women: a retrospective cohort study

Table 4 Associations between thyroid status and the risk of GDM

	Number of events/total (%)	Model 1			Model 2
	Number of events/total (%)	OR	95%CI	P	OR	95%CI	P
Thyroid function
Euthyroid & TPO Ab- (reference group)	293/2208 (13.3)	1.00	-	-	1.00	-	-
Euthyroid & TPO Ab +	28/198 (14.1)	1.08	(0.71, 1.64)	0.730	0.98	(0.64, 1.51)	0.925
Subclinical hypothyroidism	3/27 (11.1)	0.82	(0.24, 2.73)	0.743	0.85	(0.25, 2.90)	0.794
Hyperthyroidism (including subclinical)	17/115 (14.8)	1.13	(0.69, 1.93)	0.642	1.00	(0.58, 1.72)	0.987
Isolated hypothyroxinaemia	40/301 (13.3)	1.00	(0.70, 1.43)	0.993	1.03	(0.72, 1.49)	0.858
TPO Ab positivity (vs. negativity)	235/2849 (8.2)	0.98	(0.66, 1.46)	0.932	0.88	(0.59, 1.32)	0.536
TSH ≥ 2.5 mU/L (vs. < 2.5 mIU/L)	369/2849 (13.0)	1.01	(0.73, 1.39)	0.967	1.12	(0.81, 1.56)	0.486

Logistic regression analysis were operated for exploration of associations. Model 1: without adjustment. Model 2: adjusted for age, BMI, parity, gestational week of thyroid indicators measurement, and gestational week of BMI

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