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Table 3 Association between CLT and clinicopathological characteristics in patients ≥ 55 years

From: Coexisting CLT in PTC is an independent predictor of tumor aggressiveness for patients aged under 55: a retrospective analysis of 635 patients

Charateristics

Total

non-CLT(%)

CLT-coexisted(%)

OR(95%CI)

P value

Number of patients

120

81 (67.5)

39 (32.5)

  

Sex

Female

101

65 (80.2)

36 (92.3)

3.0 (0.8–10.8)

0.09

Male

19

16 (19.8)

3 (7.7)

  

Small lesion (Dmax ≤ 1 cm)

61

40 (49.4)

21 (53.8)

0.8 (0.4–1.8)

0.29

#Mean rank of lesion size

 

60.97

59.53

 

0.817

0 < size ≤ 1 cm

 

40 (49.4)

21 (53.8)

 

1 cm < size ≤ 2 cm

 

18 (22.2)

6 (15.4)

 

2 cm < size ≤ 4 cm

 

20 (24.7)

11 (28.2)

 

4 cm < size

 

3 (3.7)

1 (2.6)

 

Extrathyroidal extension

27

20 (24.7)

7 (17.9)

0.7 (0.3–1.7)

0.41

CLNM

24

17 (21.0)

7 (17.9)

0.8 (0.3–2.2)

0.7

LLNM

1

1 (1.2)

0

(0.9–1.0)

0.49

CLNM of small lesions

4

3 (6.3)

1 (4.5)

0.7 (0.1–7.3)

0.63

TNM stage

I

108

72 (88.9)

36 (92.3)

0.7 (0.2–2.6)

0.56

II-IV

12

9 (11.1)

3 (7.7)

  

Multifocality

42

31 (38.3)

11 (28.9)

0.7 (0.3–1.5)

0.32

  1. CLNM central lymph node metastasis, LLNM lateral lymph node metastasis, OR odds ratio, #Mann–Whitney U test used