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Table 1 Clinicopathological characteristics of non-CLT and CLT-coexisted groups in all patients involved

From: Coexisting CLT in PTC is an independent predictor of tumor aggressiveness for patients aged under 55: a retrospective analysis of 635 patients

Characteristics

Total

non-CLT(%)

CLT-coexisted(%)

OR(95%CI)

P value

Number of patients

635

447 (70.1)

188 (29.6)

  

Sex

Female

484

315 (70.5)

169 (89.9)

3.7 (2.2–6.2)

 < 0.001

Male

151

132 (29.5)

19 (10.1)

  

Age

 < 55

515

366 (71.1)

149 (28.9)

1.1 (0.8–1.6)

0.49

 ≥ 55

120

81 (67.5)

39 (32.5)

  

#Mean rank of lesion size

 

307.67

342.55

 

0.017

0 < size ≤  1 cm

 

240 (53.7)

85 (45.2)

  

1 cm < size ≤ 2 cm

 

95 (21.3)

38 (20.2)

2 cm < size ≤ 4 cm

 

108 (24.2)

61 (32.4)

4 cm < size

 

4 (0.9)

4 (2.1)

Small lesion (Dmax ≤ 1 cm)

325

240 (53.7)

85 (45.2)

1.4 (1.0–2.0)

0.05

Extrathyroidal extension

143

94 (21.0)

49 (26.1)

1.3 (0.9–2.0)

0.17

CLNM

297

219 (49.0)

78 (41.5)

0.7 (0.5–1.0)

0.08

LLNM

54

40 (8.9)

14 (7.4)

0.8 (0.4–1.5)

0.54

CLNM of small lesions

145

119(40.3)

26 (24.3)

0.5 (0.3–0.8)

0.003

TNM stage

I

623

438 (98.0)

185 (98.4)

0.8 (0.2–2.9)

0.72

II-IV

12

9 (2.0)

3 (1.6)

  

Multifocality

194

133 (29.8)

61 (33.0)

1.2 (0.8–1.7)

0.43

MACIS score

 < 6

595

417 (93.3)

178 (94.7)

1.3 (0.6–2.7)

0.51

6–6.99

31

24 (5.4)

7 (3.7)

0.7 (0.3–1.6)

0.38

7–7.99

9

6 (1.3)

3 (1.6)

1.2 (0.3–4.8)

0.81

High-risk recurrence

143

94 (21.0)

49 (26.1)

1.3 (0.9–2.0)

0.17

  1. CLNM central lymph node metastasis, LLNM lateral lymph node metastasis. OR odds ratio, #Mann–Whitney U test used