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Table 2 Percent of changes from baseline (before bariatric surgery) to 12 months after surgery in clinical characteristics, levels of adipokines and metabolic indices in patients with and without metabolic syndrome

From: Changes in adipokine levels and metabolic profiles following bariatric surgery

Indices Change in 12 months MS+ patients mean % change (95% CI) Change in 12 months MS- patients mean % change (95% CI) P-value for MS+ patients P-value for MS- patients
BMI (kg/m2) -30.4 (-23.4 to -37.3) -46.3 (-61.6 to -30.9) p<0.001 p<0.001
hs-CRP (mg/ml) -62.5 (-42.7 to -82.2) -300 (-592 to -7,9) p<0.001 p<0.001
Cholesterol (mmol/l) -12.5 (-18.2 to -6.7) 3.8 (-2.2 to 9.8) P=0.031 NS
LDL-Cholesterol (mmol/l) -14.1 (-41.6 to 13.4) -9.8 (-22.8 to 3.2) P=0.009 NS
HDL-Cholesterol (mmol/l) 32.8 (10.8 to 54.7) 32.7 (12.2 to 53.1) P=0.007 P=0.026
Triglycerides (mmol/l) -37.2 (-26.2 to -48.2) -16.5 (-53.9 to 20.9) P=0.005 NS
Glucose (mmol/l) -23.0 (-31.7 to -14.2 ) -13.7 (-22.7 to -4.6) P=0.040 P=0.049
A1C (%) -20.1 (-11.38 to -28.8) -9.2 (-18.3 to -0.07) P=0.003 p=0.038
A1C (IFCC) (mmol/l) -13.5 (-6.8 to -20.1) -5.0 (-10.5 to -0.4) P=0.003 P=0.041
Vitamin D (nmol/l) 8.53 (-9.5 to 26.5) 40.3 (9.2-71.3) NS P=0.05
Adiponectin (μg/ml) 118.0 (81.1-154.8) 81.4 (55.0 to 107.7) P<0.001 P=0.032
Resistin (ng/ml) 15.3 (-5.3 to 35.9) 6.3 (-21.7 to 34.4) NS NS
Leptin (ng/ml) -65.4 (-84.2 to -46.5) -78.4 (-90.3 to -66.4) P<0.001 P<0.001
Vitamin B12 (pmol/l) 41.92 (-27.3 to 111.2) -14.3 (-32.9 to 4.3) NS NS
Vitamin B9 (nmol/l) 63.8 (17.6-109.9) 41.8 (-24.1 to 107.7) P=0.022 NS
Ferritin (μg/l) -16.1 (-56.6 to 24.4) -23.0 (-55.6 to 9.6) NS NS
Fe (μmol/l) 33.6 (-18.05 to 85.2) 43.2 (-9.6 to 96.8) NS NS
  1. BMI body mass index, MS metabolic syndrome, hsCRP C-reactive protein, A1C glycated hemoglobinm, LDL-cholesterol low density cholesterol, HDL-cholesterol high density cholesterol, ND not detected, NS not significant, Fe iron