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Table 2 Percent of changes from baseline (before bariatric surgery) to 12 months after surgery in clinical characteristics, levels of adipokines and metabolic indices in patients with and without metabolic syndrome

From: Changes in adipokine levels and metabolic profiles following bariatric surgery

Indices

Change in 12 months MS+ patients mean % change (95% CI)

Change in 12 months MS- patients mean % change (95% CI)

P-value for MS+ patients

P-value for MS- patients

BMI (kg/m2)

-30.4 (-23.4 to -37.3)

-46.3 (-61.6 to -30.9)

p<0.001

p<0.001

hs-CRP (mg/ml)

-62.5 (-42.7 to -82.2)

-300 (-592 to -7,9)

p<0.001

p<0.001

Cholesterol (mmol/l)

-12.5 (-18.2 to -6.7)

3.8 (-2.2 to 9.8)

P=0.031

NS

LDL-Cholesterol (mmol/l)

-14.1 (-41.6 to 13.4)

-9.8 (-22.8 to 3.2)

P=0.009

NS

HDL-Cholesterol (mmol/l)

32.8 (10.8 to 54.7)

32.7 (12.2 to 53.1)

P=0.007

P=0.026

Triglycerides (mmol/l)

-37.2 (-26.2 to -48.2)

-16.5 (-53.9 to 20.9)

P=0.005

NS

Glucose (mmol/l)

-23.0 (-31.7 to -14.2 )

-13.7 (-22.7 to -4.6)

P=0.040

P=0.049

A1C (%)

-20.1 (-11.38 to -28.8)

-9.2 (-18.3 to -0.07)

P=0.003

p=0.038

A1C (IFCC) (mmol/l)

-13.5 (-6.8 to -20.1)

-5.0 (-10.5 to -0.4)

P=0.003

P=0.041

Vitamin D (nmol/l)

8.53 (-9.5 to 26.5)

40.3 (9.2-71.3)

NS

P=0.05

Adiponectin (μg/ml)

118.0 (81.1-154.8)

81.4 (55.0 to 107.7)

P<0.001

P=0.032

Resistin (ng/ml)

15.3 (-5.3 to 35.9)

6.3 (-21.7 to 34.4)

NS

NS

Leptin (ng/ml)

-65.4 (-84.2 to -46.5)

-78.4 (-90.3 to -66.4)

P<0.001

P<0.001

Vitamin B12 (pmol/l)

41.92 (-27.3 to 111.2)

-14.3 (-32.9 to 4.3)

NS

NS

Vitamin B9 (nmol/l)

63.8 (17.6-109.9)

41.8 (-24.1 to 107.7)

P=0.022

NS

Ferritin (μg/l)

-16.1 (-56.6 to 24.4)

-23.0 (-55.6 to 9.6)

NS

NS

Fe (μmol/l)

33.6 (-18.05 to 85.2)

43.2 (-9.6 to 96.8)

NS

NS

  1. BMI body mass index, MS metabolic syndrome, hsCRP C-reactive protein, A1C glycated hemoglobinm, LDL-cholesterol low density cholesterol, HDL-cholesterol high density cholesterol, ND not detected, NS not significant, Fe iron