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Fig. 7 | BMC Endocrine Disorders

Fig. 7

From: Maslinic acid activates renal AMPK/SIRT1 signaling pathway and protects against diabetic nephropathy in mice

Fig. 7

Maslinic acid treatment for 8 weeks activated renal AMPK/SIRT1 signaling pathway in mice model of diabetic nephropathy. Western blotting was used to measure the protein expressions of p-AMPK, AMPK and SIRT1 (a) and the relative expressions were normalized to NC. N = 10 for each group. Data are presented as mean ± SD. ###p < 0.001 compared to NC group, ***p < 0.001 compared to STZ group. A The western blotting assay was used to measure the protein expressions of p-AMPK, AMPK and SIRT1 in renal tissues of mice in STZ, MA20 and NC group. All the blots in the above figure were arranged from left to right in the order of NC, STZ, and MA20. The three blots on the left side of the upper half of the picture were p-AMPK, and the blots on right side were AMPK. The top three blots in the lower half of the picture were SIRT1, and the bottom three blots were beta-actin

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