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Fig. 6 | BMC Endocrine Disorders

Fig. 6

From: Maslinic acid activates renal AMPK/SIRT1 signaling pathway and protects against diabetic nephropathy in mice

Fig. 6

Effects of 20 mg/kg maslinic acid treatment for 8 weeks on renal inflammatory responses in mice model of diabetic nephropathy. Levels of IL-6 (a), MCP-1 (b) and TNF-α (c) in the renal tissues of diabetic nephropathy mice. mRNA levels of IL-6 (d), MCP-1 (e) and TNF-α (f) in the renal tissues were tested by qRT-PCR. Relative expression pattern was analyzed by comparative threshold cycle (2-ΔΔct) method and normalized to NC group. N = 10 for each group. Data are presented as mean ± SD. ##p < 0.01, ###p < 0.001 compared to NC group, **p < 0.01 and ***p < 0.001 compared to STZ group

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