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Table 1 The diagnostic criteria of IgG4-related hypophysitis

From: Sellar germinoma mimicking IgG4-related hypophysitis: a case report

 

2011 Laporati [10]a

2020 Japan [11]

Definitive

Probable

Possible

Symptoms due to mass effects, hypopituitarism, or central diabetes insipidus

 

Laboratory findings of hypopituitarism

 

 

 

Decreased response in stimulation tests

 

 

Laboratory findings of central diabetes insipidus

 

 

 

Image findings: pituitary enlargement/mass, stalk thickening

 

Elevated serum IgG4

 

 

Pathology of pituitary

  

 

Pathology of other involved organs

 

 

 

Response to glucocorticoids

 

 
  1. a. IgG4-related hypophysitis can be diagnosed when all items in any of the columns are fulfilled