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Table 2 Recent level 1 evidence confirming the superiority of bariatric surgery (BS) over medical therapy as a treatment of type 2 diabetes mellitus (T2DM)

From: The many faces of diabetes. Is there a need for re-classification? A narrative review

Khorgami et al. 2019 [94] Meta-analysis of 7 RCTs found that the chance of remission of T2DM was significantly higher after BS compared with medical management after at least 2-year follow-up (risk ratio (RR) = 10, 95% CI 5.5-17.9, p < 0.001).
Sharples & Mahawar 2020 [95] A meta-analysis examining 5-year outcomes reported that the resolution of T2DM was 37.4 and 27.5% after RYGB and SG respectively.
Mingrone et al. 2021 [96] RCT showed the 10-year remission rates for T2DM were significantly higher in the surgical group (BPD 50%, RYGB 25%, medical therapy 5.5%)
  1. Abbreviations: RCT Randomised controlled trial, T2DM type 2 diabetes mellitus, BS bariatric surgery, RYGB Roux en Y Gastric Bypass, SG Sleeve Gastrectomy, BPD Biliopancreatic diversion