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Table 1 Clinical and pathological characteristics of PTC patients

From: Lymph node metastasis of papillary thyroid carcinoma in the context of Hashimoto’s thyroiditis

Characteristic Total
(n = 444)
HT
(n = 150, 33.8%)
Non-HT
(n = 294, 66.2%)
P
Age, years 44.2 ± 11.7 42.3 ± 11.4 45.1 ± 11.7 0.02a
Sex, n (%)     < 0.01b
 Male 116 (26.1) 17 (11.3) 99 (33.7)  
 Female 328 (73.9) 133 (88.7) 195 (66.3)  
TSH level, μIU/mL   3.49
(1.97,5.20)
2.23
(1.55,3.31)
< 0.01c
TPO-Ab level, IU/mL   184.15 (82.40,427.55) 11.00
(9.00,15.02)
< 0.01c
TG-Ab level, IU/mL   284.20 (73.99,554.65) 12.00 (10.00,18.20) < 0.01c
Tumor-size, mm 9.80
(6.90,14.08)
9.00
(7.00,13.00)
10.00
(7.00,14.00)
0.04c
Papillary microcarcinoma, n (%)     0.04b
 No 207 (46.6) 59 (39.3) 148 (50.3)  
 Yes 237 (53.4) 91 (60.7) 146 (49.7)  
Multifocality, n (%)     0.83b
 Yes 133 (30.0) 46 (30.7) 87 (29.6)  
 No 311 (70.0) 104 (69.3) 207 (70.4)  
Lymph node metastasis, n (%)     0.93d
 Positive 221 (49.8) 72 (48.0) 149 (50.7)  
  Central only 170 (38.3) 57 (38.0) 113 (38.4)  
  Lateral only 7 (1.6) 2 (1.3) 5 (1.7)  
  Central+ Lateral 44 (9.9) 13 (8.7) 31 (10.5)  
 Negative 223 (50.2) 78 (52.0) 145 (49.3)  
Extrathyroidal extension, n (%)     1.00d
 Yes 6 (1.4) 2 (1.3) 4 (1.4)  
 No 438 (98.6) 148 (98.7) 290 (98.6)  
Distant metastasis, n (%) 0 (0)    
TNM Stage, n (%)     < 0.01d
 I 401 (90.3) 144 (96.0) 257 (87.4)  
 II 37 (8.3) 4 (2.7) 33 (11.2)  
 III 6 (1.4) 2 (1.3) 4 (1.4)  
  1. aStudent t test
  2. bχ2 test
  3. cMann-Whitney U test
  4. dFisher’s exact test