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Table 1 Clinical and pathological characteristics of PTC patients

From: Lymph node metastasis of papillary thyroid carcinoma in the context of Hashimoto’s thyroiditis

Characteristic

Total

(n = 444)

HT

(n = 150, 33.8%)

Non-HT

(n = 294, 66.2%)

P

Age, years

44.2 ± 11.7

42.3 ± 11.4

45.1 ± 11.7

0.02a

Sex, n (%)

   

< 0.01b

 Male

116 (26.1)

17 (11.3)

99 (33.7)

 

 Female

328 (73.9)

133 (88.7)

195 (66.3)

 

TSH level, μIU/mL

 

3.49

(1.97,5.20)

2.23

(1.55,3.31)

< 0.01c

TPO-Ab level, IU/mL

 

184.15 (82.40,427.55)

11.00

(9.00,15.02)

< 0.01c

TG-Ab level, IU/mL

 

284.20 (73.99,554.65)

12.00 (10.00,18.20)

< 0.01c

Tumor-size, mm

9.80

(6.90,14.08)

9.00

(7.00,13.00)

10.00

(7.00,14.00)

0.04c

Papillary microcarcinoma, n (%)

   

0.04b

 No

207 (46.6)

59 (39.3)

148 (50.3)

 

 Yes

237 (53.4)

91 (60.7)

146 (49.7)

 

Multifocality, n (%)

   

0.83b

 Yes

133 (30.0)

46 (30.7)

87 (29.6)

 

 No

311 (70.0)

104 (69.3)

207 (70.4)

 

Lymph node metastasis, n (%)

   

0.93d

 Positive

221 (49.8)

72 (48.0)

149 (50.7)

 

  Central only

170 (38.3)

57 (38.0)

113 (38.4)

 

  Lateral only

7 (1.6)

2 (1.3)

5 (1.7)

 

  Central+ Lateral

44 (9.9)

13 (8.7)

31 (10.5)

 

 Negative

223 (50.2)

78 (52.0)

145 (49.3)

 

Extrathyroidal extension, n (%)

   

1.00d

 Yes

6 (1.4)

2 (1.3)

4 (1.4)

 

 No

438 (98.6)

148 (98.7)

290 (98.6)

 

Distant metastasis, n (%)

0 (0)

   

TNM Stage, n (%)

   

< 0.01d

 I

401 (90.3)

144 (96.0)

257 (87.4)

 

 II

37 (8.3)

4 (2.7)

33 (11.2)

 

 III

6 (1.4)

2 (1.3)

4 (1.4)

 
  1. aStudent t test
  2. bχ2 test
  3. cMann-Whitney U test
  4. dFisher’s exact test