From: Lymph node metastasis of papillary thyroid carcinoma in the context of Hashimoto’s thyroiditis
Characteristic | Total (n = 444) | HT (n = 150, 33.8%) | Non-HT (n = 294, 66.2%) | P |
---|---|---|---|---|
Age, years | 44.2 ± 11.7 | 42.3 ± 11.4 | 45.1 ± 11.7 | 0.02a |
Sex, n (%) | < 0.01b | |||
Male | 116 (26.1) | 17 (11.3) | 99 (33.7) | |
Female | 328 (73.9) | 133 (88.7) | 195 (66.3) | |
TSH level, μIU/mL | 3.49 (1.97,5.20) | 2.23 (1.55,3.31) | < 0.01c | |
TPO-Ab level, IU/mL | 184.15 (82.40,427.55) | 11.00 (9.00,15.02) | < 0.01c | |
TG-Ab level, IU/mL | 284.20 (73.99,554.65) | 12.00 (10.00,18.20) | < 0.01c | |
Tumor-size, mm | 9.80 (6.90,14.08) | 9.00 (7.00,13.00) | 10.00 (7.00,14.00) | 0.04c |
Papillary microcarcinoma, n (%) | 0.04b | |||
No | 207 (46.6) | 59 (39.3) | 148 (50.3) | |
Yes | 237 (53.4) | 91 (60.7) | 146 (49.7) | |
Multifocality, n (%) | 0.83b | |||
Yes | 133 (30.0) | 46 (30.7) | 87 (29.6) | |
No | 311 (70.0) | 104 (69.3) | 207 (70.4) | |
Lymph node metastasis, n (%) | 0.93d | |||
Positive | 221 (49.8) | 72 (48.0) | 149 (50.7) | |
Central only | 170 (38.3) | 57 (38.0) | 113 (38.4) | |
Lateral only | 7 (1.6) | 2 (1.3) | 5 (1.7) | |
Central+ Lateral | 44 (9.9) | 13 (8.7) | 31 (10.5) | |
Negative | 223 (50.2) | 78 (52.0) | 145 (49.3) | |
Extrathyroidal extension, n (%) | 1.00d | |||
Yes | 6 (1.4) | 2 (1.3) | 4 (1.4) | |
No | 438 (98.6) | 148 (98.7) | 290 (98.6) | |
Distant metastasis, n (%) | 0 (0) | |||
TNM Stage, n (%) | < 0.01d | |||
I | 401 (90.3) | 144 (96.0) | 257 (87.4) | |
II | 37 (8.3) | 4 (2.7) | 33 (11.2) | |
III | 6 (1.4) | 2 (1.3) | 4 (1.4) |