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Table 6 Serum tumor markers of subjects with and without thyroid nodules (based on PSM)

From: Adjusted association between type 2 immunity and low risk thyroid nodules: a retrospective cohort study

Variables

With thyroid nodules (N = 586)

Without thyroid nodules (N = 586)

P value

AFP (μg/L)

3.64 ± 1.92

3.61 ± 1.80

0.09

CEA (μg/L)

2.08 ± 1.28

2.12 ± 1.55

0.50

NSE (ng/mL)

11.32 ± 2.06

11.42 ± 2.10

0.59

CA19–9 (μ/L)

10.88 ± 9.21

10.53 ± 8.87

0.44

CA12–5 (μ/mL)

11.54 ± 8.10

11.09 ± 7.85

0.11

CA15–3 (μ/mL)

9.33 ± 4.37

9.58 ± 5.26

0.36

  1. Matching variables included age, gender, cigarette smoking and alcohol drinking
  2. Values represent mean ± standard deviation (X ± s)
  3. AFP alpha-fetoprotein, CEA carcinoembryonic antigen, NSE neuron-specific enolase, CA19–9 carbohydrate antigen 19–9, CA12–5 cancer antigen 125, CA15–3 cancer antigen 153
  4. *P < 0.05, **P < 0.01